A study of cytokine gene polymorphisms and protein secretion in renal transplantation

Although there is evidence that cytokine gene polymorphisms are associated with varying quantities of cytokine protein production, the exact role of these polymorphisms in allograft rejection remains unclear. In a previous study, we demonstrated a significant association between high IL-10 secretion...

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Veröffentlicht in:	Transplant immunology 2001-02, Vol.8 (4), p.237-244
Hauptverfasser:	Cartwright, N.H, Keen, L.J, Demaine, A.G, Hurlock, N.J, McGonigle, R.J, Rowe, P.A, Shaw, J.F, Szydlo, R.M, Kaminski, E.R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Amino Acid Substitution Cohort Studies Cytokine Cytokines - genetics Cytokines - secretion Follow-Up Studies Gene polymorphism Genetic Predisposition to Disease Genotype Graft Rejection - genetics Graft Rejection - metabolism Heteroduplex Analysis Histocompatibility Humans Immunosuppressive Agents - therapeutic use Interleukins - genetics Interleukins - secretion Kidney Transplantation Lymphocyte Activation - drug effects Lymphocyte Culture Test, Mixed Microsatellite Repeats Mixed lymphocyte culture Phytohemagglutinins - pharmacology Point Mutation Polymerase Chain Reaction Polymorphism, Genetic Polymorphism, Single-Stranded Conformational Rejection Renal transplantation Treatment Outcome Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - secretion
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