Resveratrol inhibits human breast cancer cell growth and may mitigate the effect of linoleic acid, a potent breast cancer cell stimulator

Resveratrol is a naturally occurring product found in grapes and wine. The effect of synthetic resveratrol on the growth of estrogen receptor (ER)-positive (KPL-1 and MCF-7) and -negative (MKL-F) human breast cancer cell lines was examined. Resveratrol at low concentrations caused cell proliferation...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2001-04, Vol.127 (4), p.258-264
Hauptverfasser:	NAKAGAWA, Hiroyuki, KIYOZUKA, Yasuhiko, UEMURA, Yoshiko, SENZAKI, Hideto, SHIKATA, Nobuaki, HIOKI, Koshiro, TSUBURA, Airo
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticarcinogenic Agents - pharmacology Antineoplastic agents Apoptosis - drug effects bcl-2 Homologous Antagonist-Killer Protein bcl-2-Associated X Protein bcl-X Protein Biological and medical sciences Breast cancer Breast Neoplasms - pathology Breast Neoplasms - prevention & control Carcinogenesis, carcinogens and anticarcinogens Cell Division - drug effects Chemotherapy Female Foods and miscellaneous Humans Linoleic Acid - antagonists & inhibitors Medical sciences Membrane Proteins - analysis Pharmacology. Drug treatments Proto-Oncogene Proteins - analysis Proto-Oncogene Proteins c-bcl-2 - analysis Receptors, Estrogen - analysis Resveratrol Stilbenes - pharmacology Tumor Cells, Cultured Tumors
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