Distinct regional distribution of human equilibrative nucleoside transporter proteins 1 and 2 (hENT1 and hENT2) in the central nervous system

Nucleoside transport processes play an important role in human cells in salvage of nucleosides used in the biosynthesis of nucleic acids and in regulating endogenous adenosine concentrations in the human central nervous system (CNS). By altering the levels of adenosine available to interact with cel...

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Veröffentlicht in:	Neuropharmacology 2001-04, Vol.40 (5), p.722-731
Hauptverfasser:	Jennings, Lori L, Hao, Chunhai, Cabrita, Miguel A, Vickers, Mark F, Baldwin, Stephen A, D. Young, James, Cass, Carol E
Format:	Artikel
Sprache:	eng
Schlagworte:	A 1 receptor A 2a receptor Adenosine Adenosine - pharmacology Amino Acid Sequence Animals Antibodies, Monoclonal Biological and medical sciences Biomarkers Carrier Proteins - metabolism Cell Membrane - drug effects Cell Membrane - metabolism Cells, Cultured Central nervous system Central Nervous System - anatomy & histology Central Nervous System - metabolism Central neurotransmission. Neuromudulation. Pathways and receptors Densitometry Electrophoresis, Polyacrylamide Gel Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Equilibrative Nucleoside Transporter 1 Equilibrative-Nucleoside Transporter 2 Erythrocyte Membrane - drug effects Fundamental and applied biological sciences. Psychology hENT1 hENT2 human equilibrative nucleoside transporter Humans Immunoblotting Membrane Proteins - metabolism Molecular Sequence Data Neurotransmitter Agents - pharmacology nucleic acids Nucleoside transport Receptor, Adenosine A2A Receptors, Purinergic P1 - metabolism Vertebrates: nervous system and sense organs
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