Estrogen and antiestrogen actions on transforming growth factorbeta (TGFbeta) in normal human breast epithelial (HBE) cells

We have previously shown that estradiol (E2) increases the growth of normal human breast epithelial (HBE) cells and the antiestrogen 4-hydroxytamoxifen (4-OHT) inhibits estrogen-induced proliferation. These effects of estrogens and antiestrogens on proliferation have also been well documented in bre...

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Veröffentlicht in:	Molecular and cellular endocrinology 2001-03, Vol.174 (1-2), p.21-30
Hauptverfasser:	Malet, C, Fibleuil, F, Mestayer, C, Mowszowicz, I, Kuttenn, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Breast - cytology Cell Division - drug effects Epithelial Cells - metabolism Estrogen Antagonists - pharmacology Estrogens - pharmacology Female Humans Protein Isoforms - metabolism Protein Isoforms - pharmacology Receptors, Estrogen - metabolism Tamoxifen - analogs & derivatives Tamoxifen - pharmacology Transforming Growth Factor beta - drug effects Transforming Growth Factor beta - metabolism Transforming Growth Factor beta - pharmacology Tumor Cells, Cultured - drug effects Tumor Cells, Cultured - pathology
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