gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia

In this review, we present evidence for the role of gamma-aminobutyric acid (GABA) neurotransmission in cerebral ischemia-induced neuronal death. While glutamate neurotransmission has received widespread attention in this area of study, relatively few investigators have focused on the ischemia-induc...

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Veröffentlicht in:	Journal of neurochemistry 2001-04, Vol.77 (2), p.353-371
Hauptverfasser:	Schwartz-Bloom, R D, Sah, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Adult Age Factors Allosteric Regulation Animals Apoptosis - drug effects Arachidonic Acid - metabolism Benzodiazepines - therapeutic use Brain Damage, Chronic - prevention & control Brain Ischemia - drug therapy Brain Ischemia - physiopathology Brain Ischemia - therapy Calcium - metabolism Callithrix Chick Embryo Chloride Channels - drug effects Chloride Channels - metabolism Chlorides - metabolism Clinical Trials as Topic Drug Evaluation, Preclinical Eicosanoids - metabolism GABA Agonists - pharmacology GABA Agonists - therapeutic use GABA Antagonists - pharmacology gamma-Aminobutyric Acid - physiology Gerbillinae Hippocampus - blood supply Hippocampus - pathology Humans Interneurons - drug effects Interneurons - pathology Ion Channels - metabolism Ion Transport Mice Models, Animal Neurons - drug effects Neurons - pathology Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Rabbits Rats Reactive Oxygen Species Receptors, GABA-A - drug effects Receptors, GABA-A - physiology Synaptic Transmission - physiology
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