Rainbow trout offspring with different resistance to viral haemorrhagic septicaemia
To study immunological and immunogenetical parameters related to resistance against viral haemorrhagic septicaemia (VHS), attempts to make gynogenetic strains of rainbow trout selected for high and low resistance to VHS were initiated in 1988. The first gynogenetic generation of inbreeding resulted...
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| Veröffentlicht in: | Fish & shellfish immunology 2001-02, Vol.11 (2), p.155-167 |
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| creator | Slierendrecht, W.J. Olesen, N.J. Juul-Madsen, H.R. Lorenzen, N. Henryon, M. Berg, P. Søndergaard, J. Koch, C. |
| description | To study immunological and immunogenetical parameters related to resistance against viral haemorrhagic septicaemia (VHS), attempts to make gynogenetic strains of rainbow trout selected for high and low resistance to VHS were initiated in 1988. The first gynogenetic generation of inbreeding resulted in the more resistant offspring E8 and the low resistance offspring K3; the K3 offspring having the same high mortality as the susceptible reference strain of outbred trout in infection trials. A second gynogenetic generation derived from the E8 strain resulted in some low resistance offspring, and two gynogenetic families in which all, or nearly all, fish survived challenge with VHS virus.
In this study, an attempt to associate the distribution of different MHC class II genotypes with low and high resistance gynogenetic offspring was performed. Two different MHC haplotypes could be distinguished, and in both low and high resistance families all three genotypes were found, which could be explained by the fact that the mother fish carried the heterozygous genotype. Although no significant differences in MHC II genotypes were found between the high and low resistance offspring, a significantly different distribution of haplotypes in the low resistance offspring was observed, that could not be explained by a one- or two-locus model. |
| doi_str_mv | 10.1006/fsim.2000.0302 |
| format | Article |
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In this study, an attempt to associate the distribution of different MHC class II genotypes with low and high resistance gynogenetic offspring was performed. Two different MHC haplotypes could be distinguished, and in both low and high resistance families all three genotypes were found, which could be explained by the fact that the mother fish carried the heterozygous genotype. Although no significant differences in MHC II genotypes were found between the high and low resistance offspring, a significantly different distribution of haplotypes in the low resistance offspring was observed, that could not be explained by a one- or two-locus model.</description><identifier>ISSN: 1050-4648</identifier><identifier>EISSN: 1095-9947</identifier><identifier>DOI: 10.1006/fsim.2000.0302</identifier><identifier>PMID: 11308077</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Brackish ; Breeding - methods ; Female ; Fish Diseases - immunology ; Fish Diseases - virology ; Freshwater ; Genes, MHC Class II - genetics ; Genetic Predisposition to Disease - classification ; Genotype ; Haplotypes ; Male ; Marine ; Oncorhynchus ; Oncorhynchus mykiss ; Oncorhynchus mykiss - classification ; Oncorhynchus mykiss - genetics ; Oncorhynchus mykiss - immunology ; Polymorphism, Restriction Fragment Length ; rainbow trout, Oncorhynchus mykiss, fish, MHC, viral haemorrhagic septicaemia, disease resistance, gynogenesis ; Rhabdoviridae Infections - immunology ; Rhabdoviridae Infections - veterinary ; Rhabdoviridae Infections - virology ; Salmo ; Selection, Genetic ; Spermatozoa - radiation effects ; viral hemorrhagic septicemia</subject><ispartof>Fish & shellfish immunology, 2001-02, Vol.11 (2), p.155-167</ispartof><rights>2001 Academic Press</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-b6078658888a4bd3fed7d13ac233ce560d8811ce876cec92643e118048b028463</citedby><cites>FETCH-LOGICAL-c371t-b6078658888a4bd3fed7d13ac233ce560d8811ce876cec92643e118048b028463</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1050464800903024$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11308077$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Slierendrecht, W.J.</creatorcontrib><creatorcontrib>Olesen, N.J.</creatorcontrib><creatorcontrib>Juul-Madsen, H.R.</creatorcontrib><creatorcontrib>Lorenzen, N.</creatorcontrib><creatorcontrib>Henryon, M.</creatorcontrib><creatorcontrib>Berg, P.</creatorcontrib><creatorcontrib>Søndergaard, J.</creatorcontrib><creatorcontrib>Koch, C.</creatorcontrib><title>Rainbow trout offspring with different resistance to viral haemorrhagic septicaemia</title><title>Fish & shellfish immunology</title><addtitle>Fish Shellfish Immunol</addtitle><description>To study immunological and immunogenetical parameters related to resistance against viral haemorrhagic septicaemia (VHS), attempts to make gynogenetic strains of rainbow trout selected for high and low resistance to VHS were initiated in 1988. The first gynogenetic generation of inbreeding resulted in the more resistant offspring E8 and the low resistance offspring K3; the K3 offspring having the same high mortality as the susceptible reference strain of outbred trout in infection trials. A second gynogenetic generation derived from the E8 strain resulted in some low resistance offspring, and two gynogenetic families in which all, or nearly all, fish survived challenge with VHS virus.
In this study, an attempt to associate the distribution of different MHC class II genotypes with low and high resistance gynogenetic offspring was performed. Two different MHC haplotypes could be distinguished, and in both low and high resistance families all three genotypes were found, which could be explained by the fact that the mother fish carried the heterozygous genotype. Although no significant differences in MHC II genotypes were found between the high and low resistance offspring, a significantly different distribution of haplotypes in the low resistance offspring was observed, that could not be explained by a one- or two-locus model.</description><subject>Animals</subject><subject>Brackish</subject><subject>Breeding - methods</subject><subject>Female</subject><subject>Fish Diseases - immunology</subject><subject>Fish Diseases - virology</subject><subject>Freshwater</subject><subject>Genes, MHC Class II - genetics</subject><subject>Genetic Predisposition to Disease - classification</subject><subject>Genotype</subject><subject>Haplotypes</subject><subject>Male</subject><subject>Marine</subject><subject>Oncorhynchus</subject><subject>Oncorhynchus mykiss</subject><subject>Oncorhynchus mykiss - classification</subject><subject>Oncorhynchus mykiss - genetics</subject><subject>Oncorhynchus mykiss - immunology</subject><subject>Polymorphism, Restriction Fragment Length</subject><subject>rainbow trout, Oncorhynchus mykiss, fish, MHC, viral haemorrhagic septicaemia, disease resistance, gynogenesis</subject><subject>Rhabdoviridae Infections - immunology</subject><subject>Rhabdoviridae Infections - veterinary</subject><subject>Rhabdoviridae Infections - virology</subject><subject>Salmo</subject><subject>Selection, Genetic</subject><subject>Spermatozoa - radiation effects</subject><subject>viral hemorrhagic septicemia</subject><issn>1050-4648</issn><issn>1095-9947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtLAzEQh4MoPqpXj5KTt62TTZqkRxFfIAg-ziGbnbWR7qYmqeJ_b5YWPIlzmWH45jfwEXLKYMoA5EWXfD-tAWAKHOodcshgPqvmc6F2x3kGlZBCH5CjlN4LJbmEfXLAGAcNSh2S5yfrhyZ80RzDOtPQdWkV_fBGv3xe0NZ3HUYcMo2YfMp2cEhzoJ8-2iVdWOxDjAv75h1NuMrelY23x2Svs8uEJ9s-Ia831y9Xd9XD4-391eVD5bhiuWokKC1nupQVTcs7bFXLuHU15w5nElqtGXOolXTo5rUUHBnTIHQDtRaST8j5JncVw8caUza9Tw6XSztgWCejFEjFFPwLMlUecSEKON2ALoaUInamyOht_DYMzOjbjL7N6NuMvsvB2TZ53fTY_uJbwQXQGwCLiE-P0STnsWhsfUSXTRv8X9k_X8yPJg</recordid><startdate>20010201</startdate><enddate>20010201</enddate><creator>Slierendrecht, W.J.</creator><creator>Olesen, N.J.</creator><creator>Juul-Madsen, H.R.</creator><creator>Lorenzen, N.</creator><creator>Henryon, M.</creator><creator>Berg, P.</creator><creator>Søndergaard, J.</creator><creator>Koch, C.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>F1W</scope><scope>H94</scope><scope>H95</scope><scope>H98</scope><scope>L.G</scope><scope>7X8</scope></search><sort><creationdate>20010201</creationdate><title>Rainbow trout offspring with different resistance to viral haemorrhagic septicaemia</title><author>Slierendrecht, W.J. ; Olesen, N.J. ; Juul-Madsen, H.R. ; Lorenzen, N. ; Henryon, M. ; Berg, P. ; Søndergaard, J. ; Koch, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-b6078658888a4bd3fed7d13ac233ce560d8811ce876cec92643e118048b028463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Animals</topic><topic>Brackish</topic><topic>Breeding - methods</topic><topic>Female</topic><topic>Fish Diseases - immunology</topic><topic>Fish Diseases - virology</topic><topic>Freshwater</topic><topic>Genes, MHC Class II - genetics</topic><topic>Genetic Predisposition to Disease - classification</topic><topic>Genotype</topic><topic>Haplotypes</topic><topic>Male</topic><topic>Marine</topic><topic>Oncorhynchus</topic><topic>Oncorhynchus mykiss</topic><topic>Oncorhynchus mykiss - classification</topic><topic>Oncorhynchus mykiss - genetics</topic><topic>Oncorhynchus mykiss - immunology</topic><topic>Polymorphism, Restriction Fragment Length</topic><topic>rainbow trout, Oncorhynchus mykiss, fish, MHC, viral haemorrhagic septicaemia, disease resistance, gynogenesis</topic><topic>Rhabdoviridae Infections - immunology</topic><topic>Rhabdoviridae Infections - veterinary</topic><topic>Rhabdoviridae Infections - virology</topic><topic>Salmo</topic><topic>Selection, Genetic</topic><topic>Spermatozoa - radiation effects</topic><topic>viral hemorrhagic septicemia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Slierendrecht, W.J.</creatorcontrib><creatorcontrib>Olesen, N.J.</creatorcontrib><creatorcontrib>Juul-Madsen, H.R.</creatorcontrib><creatorcontrib>Lorenzen, N.</creatorcontrib><creatorcontrib>Henryon, M.</creatorcontrib><creatorcontrib>Berg, P.</creatorcontrib><creatorcontrib>Søndergaard, J.</creatorcontrib><creatorcontrib>Koch, C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Aquaculture Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>MEDLINE - Academic</collection><jtitle>Fish & shellfish immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Slierendrecht, W.J.</au><au>Olesen, N.J.</au><au>Juul-Madsen, H.R.</au><au>Lorenzen, N.</au><au>Henryon, M.</au><au>Berg, P.</au><au>Søndergaard, J.</au><au>Koch, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rainbow trout offspring with different resistance to viral haemorrhagic septicaemia</atitle><jtitle>Fish & shellfish immunology</jtitle><addtitle>Fish Shellfish Immunol</addtitle><date>2001-02-01</date><risdate>2001</risdate><volume>11</volume><issue>2</issue><spage>155</spage><epage>167</epage><pages>155-167</pages><issn>1050-4648</issn><eissn>1095-9947</eissn><abstract>To study immunological and immunogenetical parameters related to resistance against viral haemorrhagic septicaemia (VHS), attempts to make gynogenetic strains of rainbow trout selected for high and low resistance to VHS were initiated in 1988. The first gynogenetic generation of inbreeding resulted in the more resistant offspring E8 and the low resistance offspring K3; the K3 offspring having the same high mortality as the susceptible reference strain of outbred trout in infection trials. A second gynogenetic generation derived from the E8 strain resulted in some low resistance offspring, and two gynogenetic families in which all, or nearly all, fish survived challenge with VHS virus.
In this study, an attempt to associate the distribution of different MHC class II genotypes with low and high resistance gynogenetic offspring was performed. Two different MHC haplotypes could be distinguished, and in both low and high resistance families all three genotypes were found, which could be explained by the fact that the mother fish carried the heterozygous genotype. Although no significant differences in MHC II genotypes were found between the high and low resistance offspring, a significantly different distribution of haplotypes in the low resistance offspring was observed, that could not be explained by a one- or two-locus model.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>11308077</pmid><doi>10.1006/fsim.2000.0302</doi><tpages>13</tpages></addata></record> |
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| subjects | Animals Brackish Breeding - methods Female Fish Diseases - immunology Fish Diseases - virology Freshwater Genes, MHC Class II - genetics Genetic Predisposition to Disease - classification Genotype Haplotypes Male Marine Oncorhynchus Oncorhynchus mykiss Oncorhynchus mykiss - classification Oncorhynchus mykiss - genetics Oncorhynchus mykiss - immunology Polymorphism, Restriction Fragment Length rainbow trout, Oncorhynchus mykiss, fish, MHC, viral haemorrhagic septicaemia, disease resistance, gynogenesis Rhabdoviridae Infections - immunology Rhabdoviridae Infections - veterinary Rhabdoviridae Infections - virology Salmo Selection, Genetic Spermatozoa - radiation effects viral hemorrhagic septicemia |
| title | Rainbow trout offspring with different resistance to viral haemorrhagic septicaemia |
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