LIS1: cellular function of a disease-causing gene

Brain development is severely defective in children with lissencephaly. The highly organized distribution of neurons within the cerebral cortex is disrupted, a condition that might arise from improper migration of neuronal progenitors to their cortical destinations. Type I lissencephaly results from...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in cell biology 2001-04, Vol.11 (4), p.155-160
Hauptverfasser:	Vallee, Richard B, Tai, Chin-Yin, Faulkner, Nicole E
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Alkyl-2-acetylglycerophosphocholine Esterase Brain - abnormalities Brain - metabolism Brain - pathology Brain Diseases, Metabolic, Inborn - genetics Child cytoplasmic dynein Developmental Disabilities dynein Humans LIS1 gene lissencephaly microtubule Microtubule-Associated Proteins - deficiency Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - physiology mitosis neuronal migration platelet-activating factor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!