Dietary cosupplementation with vitamin E and coenzyme Q(10) inhibits atherosclerosis in apolipoprotein E gene knockout mice

Intimal oxidation of LDL is considered an important early event in atherogenesis, and certain antioxidants are antiatherogenic. Dietary coenrichment with vitamin E (VitE) plus ubiquinone-10 (CoQ(10), which is reduced during intestinal uptake to the antioxidant ubiquinol-10, CoQ(10)H(2)) protects, wh...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2001-04, Vol.21 (4), p.585-593
Hauptverfasser:	Thomas, S R, Leichtweis, S B, Pettersson, K, Croft, K D, Mori, T A, Brown, A J, Stocker, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - analysis Aorta - chemistry Aortic Diseases - diet therapy Aortic Diseases - prevention & control Apolipoproteins E - deficiency Apolipoproteins E - genetics Arteriosclerosis - blood Arteriosclerosis - diet therapy Arteriosclerosis - prevention & control Cholesterol, VLDL - blood Coenzymes Dietary Fats - administration & dosage Disease Models, Animal Lipids - blood Mice Mice, Inbred C57BL Mice, Knockout Ubiquinone - administration & dosage Ubiquinone - analogs & derivatives Vitamin E - administration & dosage
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