Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamine: representatives of a novel therapeutic class

The alpha-ethyl phenethylamine derivative 1-(1,3-benzodioxol-5-yl)-2-butanamine was prepared. An asymmetric synthesis was used to prepare the enantiomers of this compound and the related alpha-methyl homologue (MDA). The racemates and enantiomers of both compounds were evaluated in the two-lever dru...

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Veröffentlicht in:Journal of medicinal chemistry 1986-10, Vol.29 (10), p.2009-2015
Hauptverfasser: Nichols, D E, Hoffman, A J, Oberlender, R A, Jacob, 3rd, P, Shulgin, A T
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Sprache:eng
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