Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature

The efficacy of novel cancer therapeutics can be hampered by inefficient delivery of agents to the tumor at effective concentrations. Liposomes have been used as a method to overcome some delivery issues and, in combination with hyperthermia, have been shown to increase drug delivery to tumors. This...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2001-04, Vol.61 (7), p.3027-3032
Hauptverfasser:	KONG, Garheng, BRAUN, Rod D, DEWHIRST, Mark W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Capillary Permeability Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Female Hyperthermia, Induced Liposomes - blood Liposomes - pharmacokinetics Medical sciences Mice Mice, Nude Ovarian Neoplasms - blood supply Particle Size Pharmacology. Drug treatments Polyethylene Glycols - pharmacokinetics Temperature Xenograft Model Antitumor Assays
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