CXCR3 Chemokine Receptor Distribution in Normal and Inflamed Tissues: Expression on Activated Lymphocytes, Endothelial Cells, and Dendritic Cells

Using new human CXCR3 chemokine receptor–specific monoclonal antibodies, we studied human CXCR3 tissue distribution in lymphoid and nonlymphoid organs, as well as in inflammatory conditions, including rheumatoid arthritis, Hashimoto's thyroiditis, and dermal vasculitis. CXCR3 was expressed by c...

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Veröffentlicht in:	Laboratory investigation 2001-03, Vol.81 (3), p.409-418
Hauptverfasser:	García-López, María Ángeles, Sánchez-Madrid, Francisco, Rodríguez-Frade, Jose Miguel, Mellado, Mario, Acevedo, Agustín, García, M Isabel, Albar, Juan Pablo, Martínez-A, Carlos, Marazuela, Mónica
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Antibody Specificity Biological and medical sciences Cell physiology Cells, Cultured Chemotaxis, Leukocyte - immunology Dendritic Cells - chemistry Dendritic Cells - immunology Endothelium, Vascular - chemistry Endothelium, Vascular - immunology Fundamental and applied biological sciences. Psychology Humans Inflammation Kidney - cytology Laboratory Medicine Lymphocyte Activation - immunology Lymphocytes - chemistry Lymphocytes - immunology Lymphoid Tissue - chemistry Lymphoid Tissue - immunology Lymphoid Tissue - pathology Medicine Medicine & Public Health Mice Molecular and cellular biology Motility and taxis Pathology Receptors, Chemokine - analysis Receptors, Chemokine - genetics Receptors, Chemokine - immunology Receptors, CXCR3 Synovitis - immunology Synovitis - pathology Thyroiditis, Autoimmune - immunology Thyroiditis, Autoimmune - pathology Transfection Vasculitis - immunology Vasculitis - pathology
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