Superoxide Scavenging Activities of Sixty Chinese Medicines Determined by an ESR Spin-Trapping Method Using Electrogenerated Superoxide

Superoxide Scavenging Activities of Sixty Chinese Medicines Determined by an ESR Spin-Trapping Method Using Electrogenerated Superoxide

Superoxide-scavenging activities of 60 kinds of Chinese harbal medicines were determined accurately by an electron spin resonance (ESR) spin-trapping technique using 5,5-dimethyl-1-pyrroline 1-oxide (DMPO) as a spin-trapping reagent. As a source of superoxide in this method, superoxide generated by...

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Veröffentlicht in:YAKUGAKU ZASSHI 2001, Vol.121(4), pp.265-270
Hauptverfasser: LIU, Wenwei, OGATA, Tateaki, SATO, Shigeyoshi, UNOURA, Kei, ONODERA, Jun-ichi
Format: Artikel
Sprache:eng
Schlagworte:
Chinese medicines
Drugs, Chinese Herbal - pharmacology
electrolysis of oxygen
Electron Spin Resonance Spectroscopy
ESR
Free Radical Scavengers
scavenging activity
superoxide
Superoxides
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container_issue 4
container_start_page 265
container_title YAKUGAKU ZASSHI
container_volume 121
creator LIU, Wenwei
OGATA, Tateaki
SATO, Shigeyoshi
UNOURA, Kei
ONODERA, Jun-ichi
description Superoxide-scavenging activities of 60 kinds of Chinese harbal medicines were determined accurately by an electron spin resonance (ESR) spin-trapping technique using 5,5-dimethyl-1-pyrroline 1-oxide (DMPO) as a spin-trapping reagent. As a source of superoxide in this method, superoxide generated by one-electron reduction of the oxygen molecule in dimethyl sulfoxide solution was used. As a result of these studies, very powerful scavenging activity was found in Chinese medicines for inflammation, diseases of blood circulation and for tumors.
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subjects Chinese medicines
Drugs, Chinese Herbal - pharmacology
electrolysis of oxygen
Electron Spin Resonance Spectroscopy
ESR
Free Radical Scavengers
scavenging activity
superoxide
Superoxides
title Superoxide Scavenging Activities of Sixty Chinese Medicines Determined by an ESR Spin-Trapping Method Using Electrogenerated Superoxide
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