Therapeutic Change of HMG-CoA Reductase Inhibitors in Patients with Coronary Artery Disease

Study Objective. To evaluate short‐term outcomes when atorvastatin was substituted for pravastatin or simvastatin in patients with coronary artery disease. Design. Open‐label, fixed‐dosage, one‐way crossover from pravastatin and simvastatin to atorvastatin. Setting. University‐affiliated hospital an...

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Veröffentlicht in:	Pharmacotherapy 2001-04, Vol.21 (4), p.410-415
Hauptverfasser:	Hilleman, Daniel E., Wurdeman, Richard L., Lenz, Thomas L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Atorvastatin Calcium Biological and medical sciences Cholesterol, LDL - blood Cohort Studies Coronary Disease - drug therapy Cost-Benefit Analysis Cross-Over Studies Drug Administration Schedule Female General and cellular metabolism. Vitamins Heptanoic Acids - administration & dosage Heptanoic Acids - economics Heptanoic Acids - therapeutic use Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage Hydroxymethylglutaryl-CoA Reductase Inhibitors - economics Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Male Medical sciences Middle Aged Pharmacology. Drug treatments Pravastatin - administration & dosage Pravastatin - economics Pravastatin - therapeutic use Pyrroles - administration & dosage Pyrroles - economics Pyrroles - therapeutic use Simvastatin - administration & dosage Simvastatin - economics Simvastatin - therapeutic use Treatment Outcome
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