IL-6 up-regulates CNTF mRNA expression and enhances neurite regeneration

Interleukin-6 (IL-6) is a neurotrophic cytokine, however, its direct effect on nerve regeneration has not been well characterized. We therefore examined the effect of IL-6 on neurite regeneration using the rat dorsal root ganglion. IL-6 significantly enhanced neurite regeneration from transected ner...

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Veröffentlicht in:	Neuroreport 2001-04, Vol.12 (5), p.1081-1085
Hauptverfasser:	Shuto, Takashi, Horie, Hidenori, Hikawa, Naoshi, Sango, Kazunori, Tokashiki, Akiko, Murata, Hidetoshi, Yamamoto, Isao, Ishikawa, Yoshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - physiology Axotomy Biological and medical sciences Ciliary Neurotrophic Factor - biosynthesis Development. Senescence. Regeneration. Transplantation Fundamental and applied biological sciences. Psychology Image Processing, Computer-Assisted Interleukin-6 - pharmacology Nerve Regeneration - drug effects Neurites - drug effects Presynaptic Terminals - drug effects Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis Up-Regulation - drug effects Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
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