Impairment of spermatogonial development and spermiation after testosterone-induced gonadotropin suppression in adult monkeys (Macaca fascicularis)

Human male hormonal contraceptive regimens do not consistently induce azoospermia, and the basis of this variable response is unclear. This study used nine adult macaque monkeys (Macaca fascicularis) given testosterone (T) implants for 20 weeks to study changes in germ cell populations in relation t...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2001-04, Vol.86 (4), p.1814-1822
Hauptverfasser:	O'DONNELL, Liza, NARULA, Anita, BALOURDOS, Georgia, GU, Yi-Qun, WREFORD, Nigel G, ROBERTSON, David M, BREMNER, William J, MCLACHLAN, Robert I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Birth control Follicle Stimulating Hormone - blood Gonadal Steroid Hormones - pharmacokinetics Gonadal Steroid Hormones - pharmacology Gonadotropins - antagonists & inhibitors Gynecology. Andrology. Obstetrics Hormonal contraception Luteinizing Hormone - blood Macaca fascicularis Male Medical sciences Sertoli Cells - physiology Sperm Count Spermatogonia - classification Spermatogonia - drug effects Spermatogonia - physiology Spermatozoa - cytology Spermatozoa - drug effects Spermatozoa - physiology Testosterone - pharmacokinetics Testosterone - pharmacology Tropical medicine
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