Characterization of Epidermal Growth Factor Receptors in Cultured Vascular Smooth Muscle Cells of Rat Aorta

Characteristics of specific receptors for epidermal growth factor (EGF) and its effect on cellular proliferation and synthesis of DNA and protein were studied in cultured vascular smooth muscle cells (VSMC) from rat aorta. Binding studies using 125I-EGF revealed the presence of high affinity binding...

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Veröffentlicht in:	Endocrinologia Japonica 1986, Vol.33(2), pp.177-184
Hauptverfasser:	TOMITA, MASAHIRO, HIRATA, YUKIO, UCHIHASHI, MASAHITO, FUJITA, TAKUO
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - drug effects Aorta - metabolism Binding, Competitive Biological and medical sciences Blood vessels and receptors Cell Division - drug effects Cell Survival - drug effects Cells, Cultured DNA - biosynthesis DNA - drug effects Epidermal Growth Factor - metabolism Epidermal Growth Factor - pharmacology ErbB Receptors - drug effects ErbB Receptors - metabolism Fundamental and applied biological sciences. Psychology Male Mice Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Rats Rats, Inbred Strains Time Factors Vertebrates: cardiovascular system
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