Oral tolerance to protein antigens
Oral tolerance is an active non‐response to antigens delivered via the oral route. Mechanisms governing tolerance induction have been well characterized in mouse. Similar studies in man are lacking, although there is evidence that tolerance can be induced. In disease states, tolerance is altered and...
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| Veröffentlicht in: | Allergy (Copenhagen) 2001-04, Vol.56 (s67), p.12-15 |
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| container_issue | s67 |
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| container_title | Allergy (Copenhagen) |
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| creator | Mayer, Lloyd Sperber, Kirk Chan, Lisa Child, Joseph Toy, Lisa |
| description | Oral tolerance is an active non‐response to antigens delivered via the oral route. Mechanisms governing tolerance induction have been well characterized in mouse. Similar studies in man are lacking, although there is evidence that tolerance can be induced. In disease states, tolerance is altered and this may account for the presence of mucosal inflammation. In food hypersensitivity there is evidence that allergens may be handled differently and this may play a role in disease expression. |
| doi_str_mv | 10.1111/j.1398-9995.2001.00904.x |
| format | Article |
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Mechanisms governing tolerance induction have been well characterized in mouse. Similar studies in man are lacking, although there is evidence that tolerance can be induced. In disease states, tolerance is altered and this may account for the presence of mucosal inflammation. 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Mechanisms governing tolerance induction have been well characterized in mouse. Similar studies in man are lacking, although there is evidence that tolerance can be induced. In disease states, tolerance is altered and this may account for the presence of mucosal inflammation. In food hypersensitivity there is evidence that allergens may be handled differently and this may play a role in disease expression.</description><subject>Administration, Oral</subject><subject>Animals</subject><subject>Antigens - administration & dosage</subject><subject>Antigens - immunology</subject><subject>Humans</subject><subject>Immune Tolerance - immunology</subject><subject>Immunity, Mucosal - immunology</subject><subject>oral tolerance; intestinal epithelium; regulatory T cells; food allergens</subject><subject>Proteins - administration & dosage</subject><subject>Proteins - immunology</subject><issn>0105-4538</issn><issn>1398-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtLw0AQgBdRbK3-BQkevCXOvppd8FKKLwj0oudlN52VlDSp2RTbf-_GFj3qMrAD882Dj5CEQkbju1tllGuVaq1lxgBoBqBBZLsTMv4pnJIxUJCpkFyNyEUIKwDImYZzMqKU6TxCY3Kz6Gyd9G2NnW1KjFmy6doeqyaxTV-9YxMuyZm3dcCr4z8hb48Pr_PntFg8vcxnRVpyzUXqGHMs5yAEt85aLz3XzitZ2qmHKYLlChDitWxKkS8l-BgOhdBUehCOT8jtYW484GOLoTfrKpRY17bBdhtMnoOgDOifIM2VYhJUBNUBLLs2hA692XTV2nZ7Q8EMIs3KDL7M4MsMIs23SLOLrdfHHVu3xuVv49FcBO4PwGdV4_7fg82sKGLCvwB-sX9M</recordid><startdate>200104</startdate><enddate>200104</enddate><creator>Mayer, Lloyd</creator><creator>Sperber, Kirk</creator><creator>Chan, Lisa</creator><creator>Child, Joseph</creator><creator>Toy, Lisa</creator><general>Munksgaard International Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>200104</creationdate><title>Oral tolerance to protein antigens</title><author>Mayer, Lloyd ; Sperber, Kirk ; Chan, Lisa ; Child, Joseph ; Toy, Lisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3934-b22b2730443abaaf5f39bf85ca6f06e0a380e0200261e3d50f50fbe44915f04b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Administration, Oral</topic><topic>Animals</topic><topic>Antigens - administration & dosage</topic><topic>Antigens - immunology</topic><topic>Humans</topic><topic>Immune Tolerance - immunology</topic><topic>Immunity, Mucosal - immunology</topic><topic>oral tolerance; intestinal epithelium; regulatory T cells; food allergens</topic><topic>Proteins - administration & dosage</topic><topic>Proteins - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mayer, Lloyd</creatorcontrib><creatorcontrib>Sperber, Kirk</creatorcontrib><creatorcontrib>Chan, Lisa</creatorcontrib><creatorcontrib>Child, Joseph</creatorcontrib><creatorcontrib>Toy, Lisa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Allergy (Copenhagen)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mayer, Lloyd</au><au>Sperber, Kirk</au><au>Chan, Lisa</au><au>Child, Joseph</au><au>Toy, Lisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oral tolerance to protein antigens</atitle><jtitle>Allergy (Copenhagen)</jtitle><addtitle>Allergy</addtitle><date>2001-04</date><risdate>2001</risdate><volume>56</volume><issue>s67</issue><spage>12</spage><epage>15</epage><pages>12-15</pages><issn>0105-4538</issn><eissn>1398-9995</eissn><abstract>Oral tolerance is an active non‐response to antigens delivered via the oral route. 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| identifier | ISSN: 0105-4538 |
| ispartof | Allergy (Copenhagen), 2001-04, Vol.56 (s67), p.12-15 |
| issn | 0105-4538 1398-9995 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Free Content; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | Administration, Oral Animals Antigens - administration & dosage Antigens - immunology Humans Immune Tolerance - immunology Immunity, Mucosal - immunology oral tolerance intestinal epithelium regulatory T cells food allergens Proteins - administration & dosage Proteins - immunology |
| title | Oral tolerance to protein antigens |
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