Dose-dependent augmentation effect of bromocriptine in a case with refractory depression
1. A 52-year-old female with refractory depression had not responded to various treatments including electroconvulsive therapy and augmentation therapy with lithium or triidothyronine. 2. Addition of bromocriptine 2.5-5 mg/day to imipramine improved her depressive symptoms. However, when the dose wa...
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| Veröffentlicht in: | Progress in neuro-psychopharmacology & biological psychiatry 2001-02, Vol.25 (2), p.457-462 |
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| container_title | Progress in neuro-psychopharmacology & biological psychiatry |
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| creator | Wada, Tadashi Kanno, Muneaki Aoshima, Toshiaki Otani, Koichi |
| description | 1.
A 52-year-old female with refractory depression had not responded to various treatments including electroconvulsive therapy and augmentation therapy with lithium or triidothyronine.
2.
Addition of bromocriptine 2.5-5 mg/day to imipramine improved her depressive symptoms. However, when the dose was increased to 15 mg/day to treat residual depressive symptoms, her clinical status deteriorated and returned to the original level. The dose reduction to 5mg/day again improved her depressive symptoms.
3.
This report confirms the augmentation effect of bromocriptine for refractory depression. It also suggests that there is no dose-dependency in this effect. |
| doi_str_mv | 10.1016/S0278-5846(01)80006-3 |
| format | Article |
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A 52-year-old female with refractory depression had not responded to various treatments including electroconvulsive therapy and augmentation therapy with lithium or triidothyronine.
2.
Addition of bromocriptine 2.5-5 mg/day to imipramine improved her depressive symptoms. However, when the dose was increased to 15 mg/day to treat residual depressive symptoms, her clinical status deteriorated and returned to the original level. The dose reduction to 5mg/day again improved her depressive symptoms.
3.
This report confirms the augmentation effect of bromocriptine for refractory depression. It also suggests that there is no dose-dependency in this effect.</description><identifier>ISSN: 0278-5846</identifier><identifier>EISSN: 1878-4216</identifier><identifier>DOI: 10.1016/S0278-5846(01)80006-3</identifier><identifier>PMID: 11294489</identifier><identifier>CODEN: PNPPD7</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>augmentation effect ; Biological and medical sciences ; bromocriptine ; Bromocriptine - therapeutic use ; Catecholaminergic system ; Depressive Disorder - drug therapy ; Depressive Disorder - physiopathology ; Depressive Disorder - therapy ; Dopamine Agonists - therapeutic use ; dose-dependency ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Electroconvulsive Therapy ; Female ; Humans ; Lithium - therapeutic use ; Medical sciences ; Middle Aged ; Neuropharmacology ; Neurotransmitters. Neurotransmission. Receptors ; Pharmacology. Drug treatments ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) ; Psychology. Psychoanalysis. Psychiatry ; Psychopharmacology ; refractory depression ; Triiodothyronine - therapeutic use</subject><ispartof>Progress in neuro-psychopharmacology & biological psychiatry, 2001-02, Vol.25 (2), p.457-462</ispartof><rights>2001</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-c0e0c4103c9e6551eab171753c9a714c134d75d33d966dbf69f9d3aacbe3de163</citedby><cites>FETCH-LOGICAL-c389t-c0e0c4103c9e6551eab171753c9a714c134d75d33d966dbf69f9d3aacbe3de163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0278-5846(01)80006-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=932887$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11294489$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wada, Tadashi</creatorcontrib><creatorcontrib>Kanno, Muneaki</creatorcontrib><creatorcontrib>Aoshima, Toshiaki</creatorcontrib><creatorcontrib>Otani, Koichi</creatorcontrib><title>Dose-dependent augmentation effect of bromocriptine in a case with refractory depression</title><title>Progress in neuro-psychopharmacology & biological psychiatry</title><addtitle>Prog Neuropsychopharmacol Biol Psychiatry</addtitle><description>1.
A 52-year-old female with refractory depression had not responded to various treatments including electroconvulsive therapy and augmentation therapy with lithium or triidothyronine.
2.
Addition of bromocriptine 2.5-5 mg/day to imipramine improved her depressive symptoms. However, when the dose was increased to 15 mg/day to treat residual depressive symptoms, her clinical status deteriorated and returned to the original level. The dose reduction to 5mg/day again improved her depressive symptoms.
3.
This report confirms the augmentation effect of bromocriptine for refractory depression. It also suggests that there is no dose-dependency in this effect.</description><subject>augmentation effect</subject><subject>Biological and medical sciences</subject><subject>bromocriptine</subject><subject>Bromocriptine - therapeutic use</subject><subject>Catecholaminergic system</subject><subject>Depressive Disorder - drug therapy</subject><subject>Depressive Disorder - physiopathology</subject><subject>Depressive Disorder - therapy</subject><subject>Dopamine Agonists - therapeutic use</subject><subject>dose-dependency</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Therapy, Combination</subject><subject>Electroconvulsive Therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Lithium - therapeutic use</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neuropharmacology</subject><subject>Neurotransmitters. Neurotransmission. Receptors</subject><subject>Pharmacology. Drug treatments</subject><subject>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopharmacology</subject><subject>refractory depression</subject><subject>Triiodothyronine - therapeutic use</subject><issn>0278-5846</issn><issn>1878-4216</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LxDAQhoMoun78BCUgiB6qmaZN05OI3yB4UMFbSJOpRrbNmnSV_fdmP9Cjp2GG550ZHkL2gZ0CA3H2xPJKZqUsxDGDE8kYExlfIyOQaVzkINbJ6BfZItsxfiQGOOObZAsgr4tC1iPyeuUjZhYn2FvsB6qnb12qenC-p9i2aAbqW9oE33kT3GRwPVLXU02Njki_3fBOA7ZBm8GHGU2LAsaYwrtko9XjiHurukNebq6fL--yh8fb-8uLh8xwWQ-ZYchMAYybGkVZAuoGKqjK1OsKCgO8sFVpObe1ELZpRd3WlmttGuQWQfAdcrTcOwn-c4pxUJ2LBsdj3aOfRlVVjMs8rxJYLkETfIzpZzUJrtNhpoCpuVK1UKrmvhQDtVCqeModrA5Mmw7tX2rlMAGHK0BHo8fJRW9c_OVqnks5P3--pDDJ-HIYVDQOe4PWhSRZWe_-eeQHzYCTuQ</recordid><startdate>20010201</startdate><enddate>20010201</enddate><creator>Wada, Tadashi</creator><creator>Kanno, Muneaki</creator><creator>Aoshima, Toshiaki</creator><creator>Otani, Koichi</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010201</creationdate><title>Dose-dependent augmentation effect of bromocriptine in a case with refractory depression</title><author>Wada, Tadashi ; Kanno, Muneaki ; Aoshima, Toshiaki ; Otani, Koichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-c0e0c4103c9e6551eab171753c9a714c134d75d33d966dbf69f9d3aacbe3de163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>augmentation effect</topic><topic>Biological and medical sciences</topic><topic>bromocriptine</topic><topic>Bromocriptine - therapeutic use</topic><topic>Catecholaminergic system</topic><topic>Depressive Disorder - drug therapy</topic><topic>Depressive Disorder - physiopathology</topic><topic>Depressive Disorder - therapy</topic><topic>Dopamine Agonists - therapeutic use</topic><topic>dose-dependency</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Therapy, Combination</topic><topic>Electroconvulsive Therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Lithium - therapeutic use</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neuropharmacology</topic><topic>Neurotransmitters. Neurotransmission. Receptors</topic><topic>Pharmacology. Drug treatments</topic><topic>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopharmacology</topic><topic>refractory depression</topic><topic>Triiodothyronine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wada, Tadashi</creatorcontrib><creatorcontrib>Kanno, Muneaki</creatorcontrib><creatorcontrib>Aoshima, Toshiaki</creatorcontrib><creatorcontrib>Otani, Koichi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Progress in neuro-psychopharmacology & biological psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wada, Tadashi</au><au>Kanno, Muneaki</au><au>Aoshima, Toshiaki</au><au>Otani, Koichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dose-dependent augmentation effect of bromocriptine in a case with refractory depression</atitle><jtitle>Progress in neuro-psychopharmacology & biological psychiatry</jtitle><addtitle>Prog Neuropsychopharmacol Biol Psychiatry</addtitle><date>2001-02-01</date><risdate>2001</risdate><volume>25</volume><issue>2</issue><spage>457</spage><epage>462</epage><pages>457-462</pages><issn>0278-5846</issn><eissn>1878-4216</eissn><coden>PNPPD7</coden><abstract>1.
A 52-year-old female with refractory depression had not responded to various treatments including electroconvulsive therapy and augmentation therapy with lithium or triidothyronine.
2.
Addition of bromocriptine 2.5-5 mg/day to imipramine improved her depressive symptoms. However, when the dose was increased to 15 mg/day to treat residual depressive symptoms, her clinical status deteriorated and returned to the original level. The dose reduction to 5mg/day again improved her depressive symptoms.
3.
This report confirms the augmentation effect of bromocriptine for refractory depression. It also suggests that there is no dose-dependency in this effect.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>11294489</pmid><doi>10.1016/S0278-5846(01)80006-3</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | augmentation effect Biological and medical sciences bromocriptine Bromocriptine - therapeutic use Catecholaminergic system Depressive Disorder - drug therapy Depressive Disorder - physiopathology Depressive Disorder - therapy Dopamine Agonists - therapeutic use dose-dependency Dose-Response Relationship, Drug Drug Therapy, Combination Electroconvulsive Therapy Female Humans Lithium - therapeutic use Medical sciences Middle Aged Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology refractory depression Triiodothyronine - therapeutic use |
| title | Dose-dependent augmentation effect of bromocriptine in a case with refractory depression |
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