The P2X7 purinergic receptor on bovine macrophages mediates mycobacterial death

P2X7 is an ATP gated purinoceptor that has been linked to various immune responses. P2X7 appears to be expressed ubiquitously in the immune system and thus may be important as an effector pathway or play significant roles in cell activation/death. 2′,3′-(4-Benzoyl)benzoyl ATP is the most potent agon...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2001-02, Vol.78 (3), p.249-262
Hauptverfasser:	Smith, Ruth A., Alvarez, Antonio J., Estes, D.Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Amino Acid Sequence Animals ATP Cattle Cell Death interleukin 1^b Macrophage Macrophages - physiology Molecular Sequence Data Mycobacterium bovis P2X7 purine P2X7 receptors Receptors, Purinergic P2 - genetics Receptors, Purinergic P2 - physiology Receptors, Purinergic P2X7 RNA, Messenger - metabolism Tuberculosis, Bovine - immunology
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