Complement Factor H Is a Serum-binding Protein for Adrenomedullin, and the Resulting Complex Modulates the Bioactivities of Both Partners

Adrenomedullin (AM) is an important regulatory peptide involved in both physiological and pathological states. We have previously demonstrated the existence of a specific AM-binding protein (AMBP-1) in human plasma. In the present study, we developed a nonradioactive ligand blotting assay, which, to...

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Veröffentlicht in:The Journal of biological chemistry 2001-04, Vol.276 (15), p.12292-12300
Hauptverfasser: Pı́o, Rubén, Martı́nez, Alfredo, Unsworth, Edward J., Kowalak, Jeffrey A., Bengoechea, José A., Zipfel, Peter F., Elsasser, Ted H., Cuttitta, Frank
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Sprache:eng
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