Cytochrome P-450 isozymes from the marine teleost Stenotomus chrysops: Their roles in steroid hydroxylation and the influence of cytochrome b5

Two new cytochrome P-450 forms were purified from liver microsomes of the marine fish Stenotomus chrysops (scup). Cytochrome P-450A ( M r = 52.5K) had a CO-ligated, reduced difference spectrum λ max at 447.5 nm, and reconstituted modest benzo[ a]pyrene hydroxylase activity (0.16 nmol/min/nmol P-450)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of biochemistry and biophysics 1986-09, Vol.249 (2), p.326-338
Hauptverfasser:	Klotz, Alan V., Stegeman, John J., Woodin, Bruce R., Snowberger, Elisabeth A., Thomas, Paul E., Walsh, Christopher
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Applied sciences Catalysis Chromatography, DEAE-Cellulose Cytochrome b Group - physiology Cytochrome P-450 Enzyme System - metabolism Cytochromes b5 Electrophoresis, Polyacrylamide Gel Enzyme Activation Exact sciences and technology Fishes - metabolism Isoenzymes - metabolism Microsomes, Liver - enzymology Other techniques and industries Steroid Hydroxylases - metabolism Substrate Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!