Two-point method for determination of aminoglycoside pharmacokinetics: theoretical and practical considerations

A method is described that utilizes any two serum concentrations obtained during a multiple dosage regimen to estimate aminoglycoside pharmacokinetics. The accuracy of this method was tested theoretically using simulated patient data. In addition, the ability of this method to estimate gentamicin ph...

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Veröffentlicht in:	Therapeutic drug monitoring 1986, Vol.8 (3), p.274-278
Hauptverfasser:	HAMILTON, R. A, MOSES SING SUM CHOW
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoglycosides - metabolism Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Gentamicins - metabolism Humans Kinetics Medical sciences Methods Models, Biological Pharmacology. Drug treatments
Online-Zugang:	Volltext
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