Lesions to Schaffer collaterals prevent ischemic death of CA1 pyramidal cells

The contribution of excitatory inputs to CA1 pyramidal cell death after ischemia was examined using rats with unilateral destruction of CA3 pyramidal cells. Intracerebroventricular injection of l-α-kainic acid (KA) was performed before the induction of transient forebrain ischemia. Five days after i...

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Veröffentlicht in:	Neuroscience letters 1986-07, Vol.68 (2), p.169-174
Hauptverfasser:	Onodera, Hiroshi, Sato, Gen, Kogure, Kyuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals autoradiography Binding Sites Brain Ischemia - pathology Brain Ischemia - physiopathology cerebral ischemia glutamate receptor Glutamates - metabolism Glutamic Acid hippocampus Hippocampus - blood supply Hippocampus - metabolism Hippocampus - pathology Kainic Acid - pharmacology Male Neural Pathways - physiopathology Rats Rats, Inbred Strains selective vulnerability
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