The effects of endurance training and exhaustive exercise on mitochondrial enzymes in tissues of the rat ( Rattus norvegicus)
The aim of the present study was to ascertain the effects of training and exhaustive exercise on mitochondrial capacities to oxidize pyruvate, 2-oxoglutarate, palmitoylcarnitine, succinate and ferrocytochrome c in various tissues of the rat. Endurance capacity was significantly increased ( P
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| Veröffentlicht in: | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology Molecular & integrative physiology, 2001-04, Vol.128 (4), p.889-896 |
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| container_title | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology |
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| creator | Terblanche, S.E Gohil, K Packer, L Henderson, S Brooks, G.A |
| description | The aim of the present study was to ascertain the effects of training and exhaustive exercise on mitochondrial capacities to oxidize pyruvate, 2-oxoglutarate, palmitoylcarnitine, succinate and ferrocytochrome c in various tissues of the rat. Endurance capacity was significantly increased (
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| doi_str_mv | 10.1016/S1095-6433(00)00344-5 |
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P<0.01) by an endurance training program over a period of 5–6 weeks. The average run time to exhaustion was 214.2±23.8 min for trained rats in comparison with 54.5±11.7 min for their untrained counterparts. Oxidative capacities were reduced in liver (
P<0.05) and brown adipose tissue (
P<0.05) as a result of endurance training. On the contrary, the oxidative capacity of skeletal muscle was slightly increased and that of heart almost unaffected except for the oxidation of palmitoylcarnitine, which was significantly reduced (
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P<0.01) by an endurance training program over a period of 5–6 weeks. The average run time to exhaustion was 214.2±23.8 min for trained rats in comparison with 54.5±11.7 min for their untrained counterparts. Oxidative capacities were reduced in liver (
P<0.05) and brown adipose tissue (
P<0.05) as a result of endurance training. On the contrary, the oxidative capacity of skeletal muscle was slightly increased and that of heart almost unaffected except for the oxidation of palmitoylcarnitine, which was significantly reduced (
P<0.05) as a result of training.</description><subject>Adipose Tissue, Brown - metabolism</subject><subject>Animals</subject><subject>Body Weight</subject><subject>Brown adipose tissue</subject><subject>Cytochrome c Group - metabolism</subject><subject>Endurance training</subject><subject>Enzymes - metabolism</subject><subject>Exhaustive exercise</subject><subject>Female</subject><subject>Gastrocnemius muscle</subject><subject>Heart</subject><subject>Ketoglutaric Acids - metabolism</subject><subject>Liver</subject><subject>Liver - metabolism</subject><subject>Mitochondria - enzymology</subject><subject>Mitochondrial enzymes</subject><subject>Muscle, Skeletal</subject><subject>Myocardium - metabolism</subject><subject>Oxidation-Reduction</subject><subject>Palmitoylcarnitine - metabolism</subject><subject>Physical Conditioning, Animal</subject><subject>Physical Endurance</subject><subject>Pyruvic Acid - metabolism</subject><subject>Rat</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Succinic Acid - metabolism</subject><issn>1095-6433</issn><issn>1531-4332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1rVDEUhoMo9kN_gpKVtIvbnnzeOyuRolUoCLWuQyY5txOZm9Qkd2iF_nfTmRGXzSYhPOe8yXkIecfgjAHT5z8YLFSnpRAnAKcAQspOvSCHTAnWtVv-sp3_IQfkqJRf0JZk8jU5YIwPXAg4JI83K6Q4juhqoWmkGP2cbXRIa7YhhnhLbfQU71d2LjVsGnyP2YWCNEU6hZrcKkWfg1232j8PExYaIq2hlBm3HWsLyLbSE3pta50LjSlv8Da4uZy-Ia9Guy74dr8fk59fPt9cfO2uvl9-u_h01TmphtppsbBiab1mCpfj4EBzYI6hVxI187zn0IPUfBS9Q-dt-43woN3gBzdoNYpj8mHX9y6n3-1d1UyhOFyvbcQ0F9P3wKXki2dBNjCl5QIaqHagy6mUjKO5y2Gy-cEwME-CzFaQeZq-ATBbQUa1uvf7gHk5of9ftTfSgI87ANs8NgGzKS5gE-JDbpKMT-GZiL9uuqHL</recordid><startdate>20010401</startdate><enddate>20010401</enddate><creator>Terblanche, S.E</creator><creator>Gohil, K</creator><creator>Packer, L</creator><creator>Henderson, S</creator><creator>Brooks, G.A</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>20010401</creationdate><title>The effects of endurance training and exhaustive exercise on mitochondrial enzymes in tissues of the rat ( Rattus norvegicus)</title><author>Terblanche, S.E ; Gohil, K ; Packer, L ; Henderson, S ; Brooks, G.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c458t-639a3bad615ebf8c06201c1ed54e61d272070462f37cecdafec3d06c8d8c865f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adipose Tissue, Brown - metabolism</topic><topic>Animals</topic><topic>Body Weight</topic><topic>Brown adipose tissue</topic><topic>Cytochrome c Group - metabolism</topic><topic>Endurance training</topic><topic>Enzymes - metabolism</topic><topic>Exhaustive exercise</topic><topic>Female</topic><topic>Gastrocnemius muscle</topic><topic>Heart</topic><topic>Ketoglutaric Acids - metabolism</topic><topic>Liver</topic><topic>Liver - metabolism</topic><topic>Mitochondria - enzymology</topic><topic>Mitochondrial enzymes</topic><topic>Muscle, Skeletal</topic><topic>Myocardium - metabolism</topic><topic>Oxidation-Reduction</topic><topic>Palmitoylcarnitine - metabolism</topic><topic>Physical Conditioning, Animal</topic><topic>Physical Endurance</topic><topic>Pyruvic Acid - metabolism</topic><topic>Rat</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Succinic Acid - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Terblanche, S.E</creatorcontrib><creatorcontrib>Gohil, K</creatorcontrib><creatorcontrib>Packer, L</creatorcontrib><creatorcontrib>Henderson, S</creatorcontrib><creatorcontrib>Brooks, G.A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Comparative biochemistry and physiology. 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P<0.01) by an endurance training program over a period of 5–6 weeks. The average run time to exhaustion was 214.2±23.8 min for trained rats in comparison with 54.5±11.7 min for their untrained counterparts. Oxidative capacities were reduced in liver (
P<0.05) and brown adipose tissue (
P<0.05) as a result of endurance training. On the contrary, the oxidative capacity of skeletal muscle was slightly increased and that of heart almost unaffected except for the oxidation of palmitoylcarnitine, which was significantly reduced (
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| ispartof | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2001-04, Vol.128 (4), p.889-896 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adipose Tissue, Brown - metabolism Animals Body Weight Brown adipose tissue Cytochrome c Group - metabolism Endurance training Enzymes - metabolism Exhaustive exercise Female Gastrocnemius muscle Heart Ketoglutaric Acids - metabolism Liver Liver - metabolism Mitochondria - enzymology Mitochondrial enzymes Muscle, Skeletal Myocardium - metabolism Oxidation-Reduction Palmitoylcarnitine - metabolism Physical Conditioning, Animal Physical Endurance Pyruvic Acid - metabolism Rat Rats Rats, Sprague-Dawley Succinic Acid - metabolism |
| title | The effects of endurance training and exhaustive exercise on mitochondrial enzymes in tissues of the rat ( Rattus norvegicus) |
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