Centrally-administered opioid selective agonists inhibit drinking in the rat

The effects of intracerebroventricular injection of mu (morphine), kappa (dynorphin-(1–13), ethylketocyclazocine, and U50,488H), and delta ([D-Pen 2,D-Pen 5]enkephalin) opioid agonists on water intake of 14 hr water deprived rats was studied. All agonists caused a dose related decrease in time spent...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1986-07, Vol.25 (1), p.77-82
Hauptverfasser:	Spencer, Robert L., Deupree, David, Hsiao, Sigmund, Mosberg, Henry I., Hruby, Victor, Burks, Thomas F., Porreca, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer Analgesics Animals Biological and medical sciences Brain - physiology Cyclazocine - analogs & derivatives Cyclazocine - pharmacology Drinking Drinking Behavior - drug effects Drinking Behavior - physiology Dynorphin Dynorphins - pharmacology Enkephalin, D-Penicillamine (2,5) Enkephalins - pharmacology Ethylketocyclazocine Male Medical sciences Morphine - pharmacology Naloxone - pharmacology Neuropharmacology Opioids Peptide Fragments - pharmacology Pharmacology. Drug treatments Pyrrolidines - pharmacology Rats Receptors, Opioid - physiology Water balance
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