Stimulation of aromatase activity by dihydrotestosterone in human skin fibroblasts

In order to study the regulation of aromatase activity by androgens in cultured fibroblasts derived from genital skin of normal prepubertal boys, aromatase activity was evaluated in the presence of various concentrations of non-aromatizable androgen DHT(5α-dihydrotestosterone). The estrogen formatio...

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Veröffentlicht in:	Journal of steroid biochemistry 1986-07, Vol.25 (1), p.165-169
Hauptverfasser:	Chabab, Aziz, Sultan, Charles, Fenart, Odile, Descomps, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatase - analysis Biological and medical sciences Cells, Cultured Cycloheximide - pharmacology Cyproterone - analogs & derivatives Cyproterone - pharmacology Cyproterone Acetate Dactinomycin - pharmacology Dihydrotestosterone - pharmacology Estrogens - biosynthesis Fibroblasts - enzymology Fundamental and applied biological sciences. Psychology Humans Male Puberty Skin - enzymology Steroid hormones. Cholecalciferol derivatives Vertebrates: endocrinology
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