Left ventricular aneurysm repair in rats: Structural, functional, and molecular consequences

Objectives: This study examined the effects of aneurysm repair in a rat model of myocardial infarction on functional indices and on the spatiotemporal distribution of cardiac contractile protein and natriuretic peptide messenger RNA. Methods: In a rat infarct model, expanded left ventricular aneurys...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2001-04, Vol.121 (4), p.750-761
Hauptverfasser:	Sakaguchi, Genichi, Young, Richard L., Komeda, Masashi, Yamanaka, Kazou, Buxton, Brian F., Louis, William J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Actins - metabolism Animals Atrial Natriuretic Factor - genetics Atrial Natriuretic Factor - metabolism Biological and medical sciences Biomarkers Cardiac Myosins DNA Probes - chemistry Female Heart Aneurysm - metabolism Heart Aneurysm - pathology Heart Aneurysm - physiopathology Heart Aneurysm - surgery Heart Septum - metabolism Heart Septum - pathology Heart Ventricles - metabolism Heart Ventricles - pathology Heart Ventricles - physiopathology Heart Ventricles - surgery In Situ Hybridization Medical sciences Myocardium - metabolism Myosin Heavy Chains - genetics Myosin Heavy Chains - metabolism Myosin Light Chains - genetics Myosin Light Chains - metabolism Organ Size Protein Precursors - genetics Protein Precursors - metabolism Rats Rats, Wistar RNA, Messenger - genetics RNA, Messenger - metabolism Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Ventricular Function, Left - physiology
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