Pancreatic insufficiency in patients with chronic graft-versus-host disease
Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other...
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Veröffentlicht in: | Bone marrow transplantation (Basingstoke) 2001-01, Vol.27 (2), p.163-166 |
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creator | AKPEK, G VALLADARES, J. L LEE, L MARGOLIS, J VOGELSANG, G. B |
description | Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other etiologies, pancreatic insufficiency should also be considered in patients with cGVHD who demonstrate malabsorption. The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition. |
doi_str_mv | 10.1038/sj.bmt.1702769 |
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Pancreatic enzyme supplements can be very effective in treating this rare condition.</description><identifier>ISSN: 0268-3369</identifier><identifier>EISSN: 1476-5365</identifier><identifier>DOI: 10.1038/sj.bmt.1702769</identifier><identifier>PMID: 11281385</identifier><identifier>CODEN: BMTRE9</identifier><language>eng</language><publisher>Basingstoke: Nature Publishing Group</publisher><subject>Adult ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Bone marrow ; Bone marrow transplantation ; Bone Marrow Transplantation - adverse effects ; Bone marrow, stem cells transplantation. Graft versus host reaction ; Child, Preschool ; Chronic Disease ; Diarrhea ; Diarrhea - diagnosis ; Diarrhea - etiology ; Etiology ; Female ; Graft versus host disease ; Graft vs Host Disease - diagnosis ; Graft vs Host Disease - etiology ; Graft vs Host Disease - physiopathology ; Graft-versus-host reaction ; Hematologic Neoplasms - therapy ; Humans ; Malabsorption ; Male ; Medical sciences ; Pancreas ; Pancreatic Diseases - diagnosis ; Pancreatic Diseases - etiology ; Pancreatic Diseases - physiopathology ; Pathogenesis ; Patients ; Stem cell transplantation ; Transfusions. Complications. Transfusion reactions. 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L</creatorcontrib><creatorcontrib>LEE, L</creatorcontrib><creatorcontrib>MARGOLIS, J</creatorcontrib><creatorcontrib>VOGELSANG, G. B</creatorcontrib><title>Pancreatic insufficiency in patients with chronic graft-versus-host disease</title><title>Bone marrow transplantation (Basingstoke)</title><addtitle>Bone Marrow Transplant</addtitle><description>Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other etiologies, pancreatic insufficiency should also be considered in patients with cGVHD who demonstrate malabsorption. The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition.</description><subject>Adult</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Bone marrow</subject><subject>Bone marrow transplantation</subject><subject>Bone Marrow Transplantation - adverse effects</subject><subject>Bone marrow, stem cells transplantation. Graft versus host reaction</subject><subject>Child, Preschool</subject><subject>Chronic Disease</subject><subject>Diarrhea</subject><subject>Diarrhea - diagnosis</subject><subject>Diarrhea - etiology</subject><subject>Etiology</subject><subject>Female</subject><subject>Graft versus host disease</subject><subject>Graft vs Host Disease - diagnosis</subject><subject>Graft vs Host Disease - etiology</subject><subject>Graft vs Host Disease - physiopathology</subject><subject>Graft-versus-host reaction</subject><subject>Hematologic Neoplasms - therapy</subject><subject>Humans</subject><subject>Malabsorption</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pancreas</subject><subject>Pancreatic Diseases - diagnosis</subject><subject>Pancreatic Diseases - etiology</subject><subject>Pancreatic Diseases - physiopathology</subject><subject>Pathogenesis</subject><subject>Patients</subject><subject>Stem cell transplantation</subject><subject>Transfusions. Complications. 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The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition.</abstract><cop>Basingstoke</cop><pub>Nature Publishing Group</pub><pmid>11281385</pmid><doi>10.1038/sj.bmt.1702769</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow Bone marrow transplantation Bone Marrow Transplantation - adverse effects Bone marrow, stem cells transplantation. Graft versus host reaction Child, Preschool Chronic Disease Diarrhea Diarrhea - diagnosis Diarrhea - etiology Etiology Female Graft versus host disease Graft vs Host Disease - diagnosis Graft vs Host Disease - etiology Graft vs Host Disease - physiopathology Graft-versus-host reaction Hematologic Neoplasms - therapy Humans Malabsorption Male Medical sciences Pancreas Pancreatic Diseases - diagnosis Pancreatic Diseases - etiology Pancreatic Diseases - physiopathology Pathogenesis Patients Stem cell transplantation Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation |
title | Pancreatic insufficiency in patients with chronic graft-versus-host disease |
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