Pancreatic insufficiency in patients with chronic graft-versus-host disease

Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other...

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Veröffentlicht in:Bone marrow transplantation (Basingstoke) 2001-01, Vol.27 (2), p.163-166
Hauptverfasser: AKPEK, G, VALLADARES, J. L, LEE, L, MARGOLIS, J, VOGELSANG, G. B
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container_end_page 166
container_issue 2
container_start_page 163
container_title Bone marrow transplantation (Basingstoke)
container_volume 27
creator AKPEK, G
VALLADARES, J. L
LEE, L
MARGOLIS, J
VOGELSANG, G. B
description Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other etiologies, pancreatic insufficiency should also be considered in patients with cGVHD who demonstrate malabsorption. The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition.
doi_str_mv 10.1038/sj.bmt.1702769
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Pancreatic enzyme supplements can be very effective in treating this rare condition.</description><identifier>ISSN: 0268-3369</identifier><identifier>EISSN: 1476-5365</identifier><identifier>DOI: 10.1038/sj.bmt.1702769</identifier><identifier>PMID: 11281385</identifier><identifier>CODEN: BMTRE9</identifier><language>eng</language><publisher>Basingstoke: Nature Publishing Group</publisher><subject>Adult ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Bone marrow ; Bone marrow transplantation ; Bone Marrow Transplantation - adverse effects ; Bone marrow, stem cells transplantation. 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L</creatorcontrib><creatorcontrib>LEE, L</creatorcontrib><creatorcontrib>MARGOLIS, J</creatorcontrib><creatorcontrib>VOGELSANG, G. B</creatorcontrib><title>Pancreatic insufficiency in patients with chronic graft-versus-host disease</title><title>Bone marrow transplantation (Basingstoke)</title><addtitle>Bone Marrow Transplant</addtitle><description>Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other etiologies, pancreatic insufficiency should also be considered in patients with cGVHD who demonstrate malabsorption. The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition.</description><subject>Adult</subject><subject>Anesthesia. 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subjects Adult
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Bone marrow
Bone marrow transplantation
Bone Marrow Transplantation - adverse effects
Bone marrow, stem cells transplantation. Graft versus host reaction
Child, Preschool
Chronic Disease
Diarrhea
Diarrhea - diagnosis
Diarrhea - etiology
Etiology
Female
Graft versus host disease
Graft vs Host Disease - diagnosis
Graft vs Host Disease - etiology
Graft vs Host Disease - physiopathology
Graft-versus-host reaction
Hematologic Neoplasms - therapy
Humans
Malabsorption
Male
Medical sciences
Pancreas
Pancreatic Diseases - diagnosis
Pancreatic Diseases - etiology
Pancreatic Diseases - physiopathology
Pathogenesis
Patients
Stem cell transplantation
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Transplantation
title Pancreatic insufficiency in patients with chronic graft-versus-host disease
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