CLINICAL STUDIES OF METHYLCOBALAMINE (CH3-B12) FOR OLIGOZOOSPERMIC PATIENTS
Methylcobalamin (CH3-B12) was administered in a dose of 3000μg/day for 3 months to 62 oligozoospermic men with a presumed disturbance in spermatogenesis. Before and after treatment the ejaculate volume, sperum density, total sperm count, sperm motility, total motile sperm count, sperm velocity, bila...
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| Veröffentlicht in: | Nippon Hinyokika Gakkai zasshi 1986/05/20, Vol.77(5), pp.701-706 |
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| container_issue | 5 |
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| container_title | Nippon Hinyokika Gakkai zasshi |
| container_volume | 77 |
| creator | Okada, Hiroshi Fujisawa, Masato Okamoto, Yasuyuki Oka, Nobutoshi Hamaguchi, Takeki Hazama, Minoru Matsumoto, Osamu Kamidono, Sadao Ishigami, Joji |
| description | Methylcobalamin (CH3-B12) was administered in a dose of 3000μg/day for 3 months to 62 oligozoospermic men with a presumed disturbance in spermatogenesis. Before and after treatment the ejaculate volume, sperum density, total sperm count, sperm motility, total motile sperm count, sperm velocity, bilateral testiculular volume, serum levels of LH, FSH and testosterone and concentrations of Zn, Mg, PAP and vitamin B12 in the seminal fluid were measured. A significant improvement after treatment was revealed in sperm density, total sperm count, sperm motility, total motile sperm count and sperm velocity. Concentration of vitamin B12 in seminal fluid was significantly elevated. Pregnancy occurred in 5 of the 62 partners, 1 of the 5 by AIH. |
| doi_str_mv | 10.5980/jpnjurol1928.77.5_701 |
| format | Article |
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Before and after treatment the ejaculate volume, sperum density, total sperm count, sperm motility, total motile sperm count, sperm velocity, bilateral testiculular volume, serum levels of LH, FSH and testosterone and concentrations of Zn, Mg, PAP and vitamin B12 in the seminal fluid were measured. A significant improvement after treatment was revealed in sperm density, total sperm count, sperm motility, total motile sperm count and sperm velocity. Concentration of vitamin B12 in seminal fluid was significantly elevated. Pregnancy occurred in 5 of the 62 partners, 1 of the 5 by AIH.</description><subject>Drug Evaluation</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Oligospermia - drug therapy</subject><subject>Pregnancy</subject><subject>Vitamin B 12 - analogs & derivatives</subject><subject>Vitamin B 12 - therapeutic use</subject><issn>0021-5287</issn><issn>1884-7110</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkM1OwkAYRSdGgwR5BJKujC6K89PpTJe1FmgslNCy0M1kOh20pPzYgYVvb5GGuHD1Le4990sOAAMEh9Tj8Gm9366P9a5CHuZDxoZUMIiuQBdx7tgMIXgNuhBiZFPM2S3oG1PmkCDGMSekAzqEOYxA2gWvQRzNosCPrTRbvkRhaiUjaxpmk7c4SJ792J9Gs9B6CCbEfkb40RolCyuJo3HyniTpPFxMo8Ca-1kUzrL0DtysZGV0v709sByFWTCx42R8emErzDxkO5xLN0eo4AxrmLsUoZy7nHuukgprviqk4xQ0V8SVUnlFQYui4TBlzMWEMNID9-fdfb37OmpzEJvSKF1Vcqt3RyNY44JijzRFei6qemdMrVdiX5cbWX8LBMXJo_jrseHEr8eGG7QPjvlGFxeqtdbkk3O-Ngf5oS-5rA-lqvR_q-30paI-ZS30lvwAPu6DRw</recordid><startdate>198605</startdate><enddate>198605</enddate><creator>Okada, Hiroshi</creator><creator>Fujisawa, Masato</creator><creator>Okamoto, Yasuyuki</creator><creator>Oka, Nobutoshi</creator><creator>Hamaguchi, Takeki</creator><creator>Hazama, Minoru</creator><creator>Matsumoto, Osamu</creator><creator>Kamidono, Sadao</creator><creator>Ishigami, Joji</creator><general>THE JAPANESE UROLOGICAL ASSOCIATION</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198605</creationdate><title>CLINICAL STUDIES OF METHYLCOBALAMINE (CH3-B12) FOR OLIGOZOOSPERMIC PATIENTS</title><author>Okada, Hiroshi ; Fujisawa, Masato ; Okamoto, Yasuyuki ; Oka, Nobutoshi ; Hamaguchi, Takeki ; Hazama, Minoru ; Matsumoto, Osamu ; Kamidono, Sadao ; Ishigami, Joji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2791-488a6b11d872e0b6511b868896cac2e8fda44d5bc36aac9dd5dd7912577623373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>1986</creationdate><topic>Drug Evaluation</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Oligospermia - drug therapy</topic><topic>Pregnancy</topic><topic>Vitamin B 12 - analogs & derivatives</topic><topic>Vitamin B 12 - therapeutic use</topic><toplevel>online_resources</toplevel><creatorcontrib>Okada, Hiroshi</creatorcontrib><creatorcontrib>Fujisawa, Masato</creatorcontrib><creatorcontrib>Okamoto, Yasuyuki</creatorcontrib><creatorcontrib>Oka, Nobutoshi</creatorcontrib><creatorcontrib>Hamaguchi, Takeki</creatorcontrib><creatorcontrib>Hazama, Minoru</creatorcontrib><creatorcontrib>Matsumoto, Osamu</creatorcontrib><creatorcontrib>Kamidono, Sadao</creatorcontrib><creatorcontrib>Ishigami, Joji</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nippon Hinyokika Gakkai zasshi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okada, Hiroshi</au><au>Fujisawa, Masato</au><au>Okamoto, Yasuyuki</au><au>Oka, Nobutoshi</au><au>Hamaguchi, Takeki</au><au>Hazama, Minoru</au><au>Matsumoto, Osamu</au><au>Kamidono, Sadao</au><au>Ishigami, Joji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CLINICAL STUDIES OF METHYLCOBALAMINE (CH3-B12) FOR OLIGOZOOSPERMIC PATIENTS</atitle><jtitle>Nippon Hinyokika Gakkai zasshi</jtitle><addtitle>Jpn. j. urol</addtitle><date>1986-05</date><risdate>1986</risdate><volume>77</volume><issue>5</issue><spage>701</spage><epage>706</epage><pages>701-706</pages><issn>0021-5287</issn><eissn>1884-7110</eissn><abstract>Methylcobalamin (CH3-B12) was administered in a dose of 3000μg/day for 3 months to 62 oligozoospermic men with a presumed disturbance in spermatogenesis. Before and after treatment the ejaculate volume, sperum density, total sperm count, sperm motility, total motile sperm count, sperm velocity, bilateral testiculular volume, serum levels of LH, FSH and testosterone and concentrations of Zn, Mg, PAP and vitamin B12 in the seminal fluid were measured. A significant improvement after treatment was revealed in sperm density, total sperm count, sperm motility, total motile sperm count and sperm velocity. Concentration of vitamin B12 in seminal fluid was significantly elevated. Pregnancy occurred in 5 of the 62 partners, 1 of the 5 by AIH.</abstract><cop>Japan</cop><pub>THE JAPANESE UROLOGICAL ASSOCIATION</pub><pmid>3747305</pmid><doi>10.5980/jpnjurol1928.77.5_701</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-5287 |
| ispartof | The Japanese Journal of Urology, 1986/05/20, Vol.77(5), pp.701-706 |
| issn | 0021-5287 1884-7110 |
| language | eng ; jpn |
| recordid | cdi_proquest_miscellaneous_77015293 |
| source | J-STAGE Free; MEDLINE |
| subjects | Drug Evaluation Female Humans Male Oligospermia - drug therapy Pregnancy Vitamin B 12 - analogs & derivatives Vitamin B 12 - therapeutic use |
| title | CLINICAL STUDIES OF METHYLCOBALAMINE (CH3-B12) FOR OLIGOZOOSPERMIC PATIENTS |
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