A RACHITT for our toolbox

A new twist on DNA shuffling increases recombination frequency and expands access to sequence space, facilitating the engineering of new protein activities.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature biotechnology 2001-04, Vol.19 (4), p.314-315
1. Verfasser: Pelletier, Joelle N
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 315
container_issue 4
container_start_page 314
container_title Nature biotechnology
container_volume 19
creator Pelletier, Joelle N
description A new twist on DNA shuffling increases recombination frequency and expands access to sequence space, facilitating the engineering of new protein activities.
doi_str_mv 10.1038/86681
format Article
fullrecord <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_77013752</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A190009402</galeid><sourcerecordid>A190009402</sourcerecordid><originalsourceid>FETCH-LOGICAL-c433t-9888eb87af718e7e2e16da10382daadb05b2b93942347039d2d2ad2ab7668ede3</originalsourceid><addsrcrecordid>eNqN0U9LwzAUAPAgitO5D-BFpqDgoTN_2iQ9lqFuMBjM6TWk7evo6JqZtDC_vZkbyrxoEkgIvyTvvSDUI3hAMJMPknNJjtAZiUIeEB7zY7_GUgSYRLyDzp1bYox5yPkp6hBCJYskPkOXSX-WDEfj-bxfGNs3re03xlSp2Vygk0JXDnr7uYtenx7nw1EwmT6Ph8kkyELGmiCWUkIqhS4EkSCAAuG53oZEc63zFEcpTWMWh5SFArM4pznVfqTCBww5sC662927tua9BdeoVekyqCpdg2mdEgITJiL6JyRCCi4i6eHNL7j0edU-CUV9k9jH7NFghxa6AlXWhWmsznzPYVVmpoai9PsJiX3V4hBvn78_OOBNA5tmoVvn1Phl9n87fTu0tzubWeOchUKtbbnS9kMRrLZ1VF9f693VPqs2XUH-o_Z_6cH1DtS6aS18gzptcIiJYiRkn6pJob8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>222280988</pqid></control><display><type>article</type><title>A RACHITT for our toolbox</title><source>MEDLINE</source><source>Nature</source><source>Alma/SFX Local Collection</source><creator>Pelletier, Joelle N</creator><creatorcontrib>Pelletier, Joelle N</creatorcontrib><description>A new twist on DNA shuffling increases recombination frequency and expands access to sequence space, facilitating the engineering of new protein activities.</description><identifier>ISSN: 1087-0156</identifier><identifier>EISSN: 1546-1696</identifier><identifier>DOI: 10.1038/86681</identifier><identifier>PMID: 11283580</identifier><language>eng</language><publisher>United States: Nature Publishing Group</publisher><subject>Crossing Over, Genetic ; directed evolution ; DNA - metabolism ; DNA shuffling ; Genetic Techniques ; Nucleic Acid Hybridization ; Polymerase Chain Reaction ; Protein Engineering ; Recombination, Genetic</subject><ispartof>Nature biotechnology, 2001-04, Vol.19 (4), p.314-315</ispartof><rights>COPYRIGHT 2001 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Apr 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c433t-9888eb87af718e7e2e16da10382daadb05b2b93942347039d2d2ad2ab7668ede3</citedby><cites>FETCH-LOGICAL-c433t-9888eb87af718e7e2e16da10382daadb05b2b93942347039d2d2ad2ab7668ede3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,2731,27933,27934</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11283580$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pelletier, Joelle N</creatorcontrib><title>A RACHITT for our toolbox</title><title>Nature biotechnology</title><addtitle>Nat Biotechnol</addtitle><description>A new twist on DNA shuffling increases recombination frequency and expands access to sequence space, facilitating the engineering of new protein activities.</description><subject>Crossing Over, Genetic</subject><subject>directed evolution</subject><subject>DNA - metabolism</subject><subject>DNA shuffling</subject><subject>Genetic Techniques</subject><subject>Nucleic Acid Hybridization</subject><subject>Polymerase Chain Reaction</subject><subject>Protein Engineering</subject><subject>Recombination, Genetic</subject><issn>1087-0156</issn><issn>1546-1696</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0U9LwzAUAPAgitO5D-BFpqDgoTN_2iQ9lqFuMBjM6TWk7evo6JqZtDC_vZkbyrxoEkgIvyTvvSDUI3hAMJMPknNJjtAZiUIeEB7zY7_GUgSYRLyDzp1bYox5yPkp6hBCJYskPkOXSX-WDEfj-bxfGNs3re03xlSp2Vygk0JXDnr7uYtenx7nw1EwmT6Ph8kkyELGmiCWUkIqhS4EkSCAAuG53oZEc63zFEcpTWMWh5SFArM4pznVfqTCBww5sC662927tua9BdeoVekyqCpdg2mdEgITJiL6JyRCCi4i6eHNL7j0edU-CUV9k9jH7NFghxa6AlXWhWmsznzPYVVmpoai9PsJiX3V4hBvn78_OOBNA5tmoVvn1Phl9n87fTu0tzubWeOchUKtbbnS9kMRrLZ1VF9f693VPqs2XUH-o_Z_6cH1DtS6aS18gzptcIiJYiRkn6pJob8</recordid><startdate>20010401</startdate><enddate>20010401</enddate><creator>Pelletier, Joelle N</creator><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>M7S</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20010401</creationdate><title>A RACHITT for our toolbox</title><author>Pelletier, Joelle N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c433t-9888eb87af718e7e2e16da10382daadb05b2b93942347039d2d2ad2ab7668ede3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Crossing Over, Genetic</topic><topic>directed evolution</topic><topic>DNA - metabolism</topic><topic>DNA shuffling</topic><topic>Genetic Techniques</topic><topic>Nucleic Acid Hybridization</topic><topic>Polymerase Chain Reaction</topic><topic>Protein Engineering</topic><topic>Recombination, Genetic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pelletier, Joelle N</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Nature biotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pelletier, Joelle N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A RACHITT for our toolbox</atitle><jtitle>Nature biotechnology</jtitle><addtitle>Nat Biotechnol</addtitle><date>2001-04-01</date><risdate>2001</risdate><volume>19</volume><issue>4</issue><spage>314</spage><epage>315</epage><pages>314-315</pages><issn>1087-0156</issn><eissn>1546-1696</eissn><abstract>A new twist on DNA shuffling increases recombination frequency and expands access to sequence space, facilitating the engineering of new protein activities.</abstract><cop>United States</cop><pub>Nature Publishing Group</pub><pmid>11283580</pmid><doi>10.1038/86681</doi><tpages>2</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1087-0156
ispartof Nature biotechnology, 2001-04, Vol.19 (4), p.314-315
issn 1087-0156
1546-1696
language eng
recordid cdi_proquest_miscellaneous_77013752
source MEDLINE; Nature; Alma/SFX Local Collection
subjects Crossing Over, Genetic
directed evolution
DNA - metabolism
DNA shuffling
Genetic Techniques
Nucleic Acid Hybridization
Polymerase Chain Reaction
Protein Engineering
Recombination, Genetic
title A RACHITT for our toolbox
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-03T12%3A35%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20RACHITT%20for%20our%20toolbox&rft.jtitle=Nature%20biotechnology&rft.au=Pelletier,%20Joelle%20N&rft.date=2001-04-01&rft.volume=19&rft.issue=4&rft.spage=314&rft.epage=315&rft.pages=314-315&rft.issn=1087-0156&rft.eissn=1546-1696&rft_id=info:doi/10.1038/86681&rft_dat=%3Cgale_proqu%3EA190009402%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=222280988&rft_id=info:pmid/11283580&rft_galeid=A190009402&rfr_iscdi=true