Infectivity of blood from PCR-positive, HBsAg-negative, anti-HBs-positive cases of resolved hepatitis B infection

BACKGROUND: Numerous reports have noted the existence of sera, particularly from resolving cases of HBV infection, that are positive for HBV DNA by PCR, despite being negative for HBsAg and IgM anti‐HBc. If such blood is infective and detectable by HBV NAT screening, it seems desirable to introduce...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2001-03, Vol.41 (3), p.329-332
Hauptverfasser:	Prince, Alfred M., Lee, Dong-Hun, Brotman, Betsy
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Blood Physiological Phenomena Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis DNA, Viral - blood Female Hepatitis B - transmission Hepatitis B Antibodies - blood Hepatitis B Surface Antigens - blood Hepatitis B virus - genetics Human viral diseases Humans Infectious diseases Male Medical sciences Monocytes - metabolism Monocytes - physiology Pan troglodytes Polymerase Chain Reaction Transfusions. Complications. Transfusion reactions. Cell and gene therapy Viral diseases Viral hepatitis
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