In vitro Transformation Elicited by Creutzfeldt-Jakob-Infected Brain Material

Previous studies indicated that tissue culture cells derived from Creutzfeldt-Jakob disease (CJD) brains possess neoplastic properties. In order to see if CJD brain material could itself transform cells in vitro, BALB/C-3T3 and normal hamster brain monolayer cultures were exposed to whole brain homo...

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Veröffentlicht in:	Journal of neuropathology and experimental neurology 1986-09, Vol.45 (5), p.489-502
Hauptverfasser:	OLESZAK, EMILIA L, MANUELIDIS, LAURA, MANUELIDIS, ELIAS E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Brain - pathology Cell Division Cell Line Cell Transformation, Neoplastic Creutzfeldt-Jakob Syndrome - pathology Cricetinae DNA - biosynthesis Human viral diseases Humans Infectious diseases Medical sciences Mice Mice, Inbred BALB C Microscopy, Electron Viral diseases Viral diseases of the nervous system
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