An improved high-performance liquid chromatographic method for the determination of sphingosine-1-phosphate in complex biological materials

Sphingosine-1-phosphate (SPP) has been proposed to act both as an intracellular second messenger and as an extracellular mediator via specific cell surface receptors. Based on the increasing diverse cellular roles methods to quantify endogenous and exogenous SPP are highly required. Here, we report...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 2001-03, Vol.363 (3), p.358-363
Hauptverfasser:	Ruwisch, L, Schäfer-Korting, M, Kleuser, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Platelets - chemistry Calcitriol - pharmacology Cell Extracts - chemistry Chromatography, High Pressure Liquid - methods HL-60 Cells - chemistry Humans Keratinocytes - chemistry Lysophospholipids Sensitivity and Specificity Sphingosine - analogs & derivatives Sphingosine - analysis Sphingosine - blood U937 Cells - chemistry
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