Synthesis of anthraquinonyl glucosaminosides and studies on the influence of aglycone hydroxyl substitution on superoxide generation, DNA binding, and antimicrobial properties
A series of anthraquinonyl glucosaminosides (10a-e) were synthesized by Koenigs-Knorr glycosidation of the corresponding aglycones (11a-e) with bromo sugar 12 followed by saponification. These glycosides were intended to serve as models to study the role played by the hydroxyl substituents on the ag...
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Veröffentlicht in: | Journal of medicinal chemistry 1986-09, Vol.29 (9), p.1709-1714 |
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Format: | Artikel |
Sprache: | eng |
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