Key peptide processing enzymes are expressed by breast cancer cells

The expression of the three key peptide processing enzyme families, represented by CPE, PAM, and PC1/3 plus PC2, were examined in MCF-7 and ZR-75-1 breast cancer cell lines. Both of these cell lines express vasopressin receptors as well as the vasopressin gene, but the processing of vasopressin gene...

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Veröffentlicht in:	Cancer letters 2001-04, Vol.165 (2), p.211-218
Hauptverfasser:	Du, Jinlin, Keegan, Brendan P., North, William G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Breast cancer Breast Neoplasms - enzymology Carboxypeptidase E Carboxypeptidase H Carboxypeptidases - biosynthesis Cloning, Molecular Furin Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Mixed Function Oxygenases - biosynthesis Multienzyme Complexes Neuropeptide Peptidylglycine α-amidating monooxygenase Processing Prohormone convertase Receptors, Vasopressin - biosynthesis Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Sequence Analysis, DNA Subtilisins - biosynthesis Tumor Cells, Cultured Tumors Vasopressin
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