Qualitative and Quantitative Changes in Cutaneous Bacteria Associated with Systemic Isotretinoin Therapy for Acne Conglobata

Quantitative cultures in 40 patients treated with systemic isotretinoin demonstrated a significant reduction in the anaerobic diphtheroid, Propionibacterium acnes within one month of therapy and a continued suppression during 5 months of treatment. This reduction persisted after discontinuation of i...

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Veröffentlicht in:	Journal of investigative dermatology 1986-04, Vol.86 (4), p.390-393
Hauptverfasser:	Leyden, James J, McGinley, Kenneth J, Foglia, Arlene N
Format:	Artikel
Sprache:	eng
Schlagworte:	Acne Acne Vulgaris - drug therapy Acne Vulgaris - microbiology Acne Vulgaris - physiopathology Aerobic bacteria Biological and medical sciences Dermatology Diphtheroids Excretion Gram-negative bacteria Humans Isotretinoin Medical sciences Pharmacology. Drug treatments Propionibacterium acnes Propionibacterium acnes - drug effects Propionibacterium acnes - growth & development Sebum - drug effects Sebum - metabolism Skin Skin - drug effects Skin - microbiology Skin, nail, hair, dermoskeleton Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - growth & development Tretinoin - therapeutic use
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