UVB/PUVA- Induced Suppression of Human Natural Killer Activity Is Reduced by Superoxide Dismutase and/or Interleukin 2 In Vitro

We have evaluated the effects of ultraviolet irradiation or PUVA treatment (8-methoxypsoralen (8-MOP) plus long-wave ultraviolet (UVA) irradiation] on natural killer (NK) activity of human peripheral blood mononuclear cells (PBMC). In vitro exposure of PBMC to UVB (280-320 nm, 1–30 mJ/cm2) or PUVA [...

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Veröffentlicht in:	Journal of investigative dermatology 1986-05, Vol.86 (5), p.519-522
Hauptverfasser:	Toda, Ken-ichi, Miyachi, Yoshiki, Nesumi, Naofumi, Konishi, Junji, Imamura, Sadao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cytotoxicity, Immunologic - drug effects Cytotoxicity, Immunologic - radiation effects Dermatology Diseases of the skin. Cosmetics Female Humans Immunosuppression Interleukin 2 Interleukin-2 - physiology Killer Cells, Natural - classification Killer Cells, Natural - drug effects Killer Cells, Natural - radiation effects Leukocyte Count - drug effects Leukocyte Count - radiation effects Male Medical sciences Natural killer cells Peripheral blood mononuclear cells Phenotype PUVA Therapy Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Superoxide dismutase Superoxide Dismutase - pharmacology U.V. radiation Ultraviolet Rays
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