Molecular cloning of a human prion protein cDNA

Creutzfeldt-Jakob disease (CJD) of humans and scrapie of animals are degenerative, transmissible neurologic diseases caused by prions. The only known macromolecules within prions are prion proteins (PrP). The cDNA encoding the hamster prion protein (PrP 27-30) has been cloned and sequenced (Oesch et...

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Veröffentlicht in:	DNA (New York, N.Y.) N.Y.), 1986-08, Vol.5 (4), p.315-324
Hauptverfasser:	Kretzschmar, H A, Stowring, L E, Westaway, D, Stubblebine, W H, Prusiner, S B, Dearmond, S J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cloning, Molecular Cricetinae DNA - genetics Humans Melanoma - genetics Nerve Tissue Proteins - genetics Prions - genetics Retinoblastoma - genetics RNA, Messenger - genetics Sequence Homology, Nucleic Acid
Online-Zugang:	Volltext
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