Increased amplifier T cell activity in autoimmune NZB mice and its possible significance in the expression of autoimmune disease

The expression of amplifier- and helper-T cell activity was examined in NZB/N mice of different ages. Amplifier T cell activity develops in a cyclic manner; it decreases between 16 and 35 wk of age and then increases to maximal levels in mice older than 50 wk of age. The loss of suppressor T cell ac...

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Veröffentlicht in:	Immunobiology (1979) 1986-07, Vol.171 (4), p.400-411
Hauptverfasser:	Baker, P.J., Fauntleroy, M.B., Stashak, P.W., McCoy, Kathleen L., Chused, T.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Antibody Formation Autoimmune Diseases - immunology Autoimmunity (experimental aspects and models) Biological and medical sciences Female Fundamental and applied biological sciences. Psychology Fundamental immunology Mice Mice, Inbred NZB - immunology Polysaccharides, Bacterial - immunology Streptococcus pneumoniae - immunology T-Lymphocytes - immunology T-Lymphocytes - transplantation T-Lymphocytes, Helper-Inducer - immunology
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