Compensatory phospholipid digestion is required for cholesterol absorption in pancreatic phospholipase A(2)-deficient mice

Numerous studies have suggested phospholipid inhibition of dietary cholesterol absorption through the gastrointestinal tract. This study addressed the importance of luminal phospholipid hydrolysis in this process. The effect of phospholipase inhibition on cholesterol transport from intestinal lumen...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2001-04, Vol.120 (5), p.1193-1202
Hauptverfasser:	Richmond, B L, Boileau, A C, Zheng, S, Huggins, K W, Granholm, N A, Tso, P, Hui, D Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbon Radioisotopes Cholesterol, Dietary - pharmacokinetics Digestive System Fistula - metabolism Female Intestinal Absorption - physiology Lymph - metabolism Male Mice Mice, Inbred C3H Mice, Inbred C57BL Mice, Knockout Phospholipases A - genetics Phospholipases A - metabolism Phospholipases A2 Pregnancy Rats Rats, Sprague-Dawley Triglycerides - pharmacokinetics
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