ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism

Background & Aims: Members of the family of ABC transporters are involved in different processes of sterol metabolism, and ABCA1 was recently identified as a key regulator of high-density lipoprotein (HDL) metabolism. Our aim was to further analyze the role of ABCA1 in cholesterol metabolism. Me...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2001-04, Vol.120 (5), p.1203-1211
Hauptverfasser:	Drobnik, Wolfgang, Lindenthal, Bernhard, Lieser, Bernd, Ritter, Mirko, Weber, Trudy Christiansen, Liebisch, Gerhard, Giesa, Uwe, Igel, Michael, Borsukova, Hana, Büchler, Christa, Fung-Leung, Wai Ping, Bergmann, Klaus Von, Schmitz, Gerd
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Binding Cassette Transporter 1 ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Bile Acids and Salts - analysis Biological and medical sciences CD36 Antigens - biosynthesis Cholesterol - biosynthesis Cholesterol - blood Cholesterol - pharmacokinetics Eating Feces - chemistry Fundamental and applied biological sciences. Psychology Intestinal Absorption - physiology Intestinal Mucosa - metabolism Lipids. Glycolipids Liver - metabolism Lung - metabolism Membrane Proteins Metabolisms and neurohumoral controls Mice Mice, Inbred C57BL Mice, Knockout Receptors, Immunologic Receptors, Lipoprotein Receptors, Scavenger Scavenger Receptors, Class B Vertebrates: anatomy and physiology, studies on body, several organs or systems
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