High-frequency ventilation versus conventional ventilation in dogs with right ventricular dysfunction
A randomized crossover protocol was used to compare conventional mechanical ventilation (CMV) and high-frequency ventilation (HFV) in mongrel dogs experiencing right ventricular dysfunction after right ventriculotomy. When inspired oxygen, pH, Pco2, core temperature, and preload were held constant,...
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| Veröffentlicht in: | Critical care medicine 1986-09, Vol.14 (9), p.798-801 |
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| creator | LUCKING, STEVEN E FIELDS, ALAN I MAHFOOD, SAADE KASSIR, M MARK MIDGLEY, FRANK M |
| description | A randomized crossover protocol was used to compare conventional mechanical ventilation (CMV) and high-frequency ventilation (HFV) in mongrel dogs experiencing right ventricular dysfunction after right ventriculotomy. When inspired oxygen, pH, Pco2, core temperature, and preload were held constant, cardiac output increased significantly (p < .05) from 1.16 ± 0.24 to 1.38 ± 0.25 L/min and pulmonary vascular resistance decreased significantly (p < .05) from 734 ± 257 to 554 ± 169 dyne sec/cm5 during HFV relative to CMV. We also noted a significant (p < .05) increase in mean arterial pressure from 116 ± 27 to 124 ± 23 mm Hg and a significant (p < .05) increase in left ventricular stroke work from 10.2 ± 3.5 to 12.3 ± 2.6 gm during HFV. During the inspiratory phase of CMV there were increases in CVP, pulmonary artery pressure, and systemic arterial pressure, and decreases in pulmonary artery flow which did not occur during HFV. HFV may be preferable to CMV in the presence of right ventricular dysfunction. |
| doi_str_mv | 10.1097/00003246-198609000-00008 |
| format | Article |
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When inspired oxygen, pH, Pco2, core temperature, and preload were held constant, cardiac output increased significantly (p < .05) from 1.16 ± 0.24 to 1.38 ± 0.25 L/min and pulmonary vascular resistance decreased significantly (p < .05) from 734 ± 257 to 554 ± 169 dyne sec/cm5 during HFV relative to CMV. We also noted a significant (p < .05) increase in mean arterial pressure from 116 ± 27 to 124 ± 23 mm Hg and a significant (p < .05) increase in left ventricular stroke work from 10.2 ± 3.5 to 12.3 ± 2.6 gm during HFV. During the inspiratory phase of CMV there were increases in CVP, pulmonary artery pressure, and systemic arterial pressure, and decreases in pulmonary artery flow which did not occur during HFV. HFV may be preferable to CMV in the presence of right ventricular dysfunction.</description><identifier>ISSN: 0090-3493</identifier><identifier>EISSN: 1530-0293</identifier><identifier>DOI: 10.1097/00003246-198609000-00008</identifier><identifier>PMID: 3743097</identifier><language>eng</language><publisher>United States: Williams & Wilkins</publisher><subject>Animals ; Blood Pressure ; Cardiac Output ; Child, Preschool ; Dogs ; Heart Diseases - physiopathology ; Heart Ventricles - physiopathology ; Heart Ventricles - surgery ; Humans ; Pulmonary Circulation ; Random Allocation ; Respiration, Artificial - methods</subject><ispartof>Critical care medicine, 1986-09, Vol.14 (9), p.798-801</ispartof><rights>Williams & Wilkins 1986. 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When inspired oxygen, pH, Pco2, core temperature, and preload were held constant, cardiac output increased significantly (p < .05) from 1.16 ± 0.24 to 1.38 ± 0.25 L/min and pulmonary vascular resistance decreased significantly (p < .05) from 734 ± 257 to 554 ± 169 dyne sec/cm5 during HFV relative to CMV. We also noted a significant (p < .05) increase in mean arterial pressure from 116 ± 27 to 124 ± 23 mm Hg and a significant (p < .05) increase in left ventricular stroke work from 10.2 ± 3.5 to 12.3 ± 2.6 gm during HFV. During the inspiratory phase of CMV there were increases in CVP, pulmonary artery pressure, and systemic arterial pressure, and decreases in pulmonary artery flow which did not occur during HFV. HFV may be preferable to CMV in the presence of right ventricular dysfunction.</description><subject>Animals</subject><subject>Blood Pressure</subject><subject>Cardiac Output</subject><subject>Child, Preschool</subject><subject>Dogs</subject><subject>Heart Diseases - physiopathology</subject><subject>Heart Ventricles - physiopathology</subject><subject>Heart Ventricles - surgery</subject><subject>Humans</subject><subject>Pulmonary Circulation</subject><subject>Random Allocation</subject><subject>Respiration, Artificial - methods</subject><issn>0090-3493</issn><issn>1530-0293</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UU1PAyEUJEZTa_UnmOzJ2yosywJH06g1MfGiZ8Iu0KIUKuza9N9LP2ziQS7wZubNyxsAKBC8RZDTO5gPruqmRJw1kOeq3ELsBIwRwbmoOD4FY5ipEtccn4OLlD4gRDWheARGmNY4-4yBntn5ojRRfw3ad5viW_veOtnb4PM7piEVXfA7NHjp_vDWFyrMU7G2_aKI2aff0dF2g5OxUJtkBt9tpZfgzEiX9NXhnoD3x4e36ax8eX16nt6_lB0mhJWoZqpinMiWooZRw1UFDTGaMkkUbiGmHBKVN-BSGsg5ZIrrupM4q5sWtXgCbva-qxjyQqkXS5s67Zz0OgxJ0IZzgpomC9le2MWQUtRGrKJdyrgRCIptwuI3YXFMeAex3Hp9mDG0S62OjYdIM1_v-XVwfU7w0w1rHcVCS9cvxH8fh38A16OIJQ</recordid><startdate>198609</startdate><enddate>198609</enddate><creator>LUCKING, STEVEN E</creator><creator>FIELDS, ALAN I</creator><creator>MAHFOOD, SAADE</creator><creator>KASSIR, M MARK</creator><creator>MIDGLEY, FRANK M</creator><general>Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198609</creationdate><title>High-frequency ventilation versus conventional ventilation in dogs with right ventricular dysfunction</title><author>LUCKING, STEVEN E ; FIELDS, ALAN I ; MAHFOOD, SAADE ; KASSIR, M MARK ; MIDGLEY, FRANK M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3558-148d2895ab71687f9d20f5fe78a5d3b037905d5739aaf09908d9e4ca31686b1b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Blood Pressure</topic><topic>Cardiac Output</topic><topic>Child, Preschool</topic><topic>Dogs</topic><topic>Heart Diseases - physiopathology</topic><topic>Heart Ventricles - physiopathology</topic><topic>Heart Ventricles - surgery</topic><topic>Humans</topic><topic>Pulmonary Circulation</topic><topic>Random Allocation</topic><topic>Respiration, Artificial - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LUCKING, STEVEN E</creatorcontrib><creatorcontrib>FIELDS, ALAN I</creatorcontrib><creatorcontrib>MAHFOOD, SAADE</creatorcontrib><creatorcontrib>KASSIR, M MARK</creatorcontrib><creatorcontrib>MIDGLEY, FRANK M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Critical care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LUCKING, STEVEN E</au><au>FIELDS, ALAN I</au><au>MAHFOOD, SAADE</au><au>KASSIR, M MARK</au><au>MIDGLEY, FRANK M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High-frequency ventilation versus conventional ventilation in dogs with right ventricular dysfunction</atitle><jtitle>Critical care medicine</jtitle><addtitle>Crit Care Med</addtitle><date>1986-09</date><risdate>1986</risdate><volume>14</volume><issue>9</issue><spage>798</spage><epage>801</epage><pages>798-801</pages><issn>0090-3493</issn><eissn>1530-0293</eissn><abstract>A randomized crossover protocol was used to compare conventional mechanical ventilation (CMV) and high-frequency ventilation (HFV) in mongrel dogs experiencing right ventricular dysfunction after right ventriculotomy. When inspired oxygen, pH, Pco2, core temperature, and preload were held constant, cardiac output increased significantly (p < .05) from 1.16 ± 0.24 to 1.38 ± 0.25 L/min and pulmonary vascular resistance decreased significantly (p < .05) from 734 ± 257 to 554 ± 169 dyne sec/cm5 during HFV relative to CMV. We also noted a significant (p < .05) increase in mean arterial pressure from 116 ± 27 to 124 ± 23 mm Hg and a significant (p < .05) increase in left ventricular stroke work from 10.2 ± 3.5 to 12.3 ± 2.6 gm during HFV. During the inspiratory phase of CMV there were increases in CVP, pulmonary artery pressure, and systemic arterial pressure, and decreases in pulmonary artery flow which did not occur during HFV. HFV may be preferable to CMV in the presence of right ventricular dysfunction.</abstract><cop>United States</cop><pub>Williams & Wilkins</pub><pmid>3743097</pmid><doi>10.1097/00003246-198609000-00008</doi><tpages>4</tpages></addata></record> |
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| ispartof | Critical care medicine, 1986-09, Vol.14 (9), p.798-801 |
| issn | 0090-3493 1530-0293 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Animals Blood Pressure Cardiac Output Child, Preschool Dogs Heart Diseases - physiopathology Heart Ventricles - physiopathology Heart Ventricles - surgery Humans Pulmonary Circulation Random Allocation Respiration, Artificial - methods |
| title | High-frequency ventilation versus conventional ventilation in dogs with right ventricular dysfunction |
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