How does oxygen inhibit central metabolism in the obligate anaerobe Bacteroides thetaiotaomicron

The molecular basis of obligate anaerobiosis is not well established. Bacteroides thetaiotaomicron is an opportunistic pathogen that cannot grow in fully aerobic habitats. Because microbial niches reflect features of energy‐producing strategies, we suspected that aeration would interfere with its ce...

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Veröffentlicht in:	Molecular microbiology 2001-03, Vol.39 (6), p.1562-1571
Hauptverfasser:	Pan, Ning, Imlay, James A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteroides - metabolism Bacteroides thetaiotaomicron Enzyme Activation Fermentation Fumarate Hydratase - metabolism Iron-Sulfur Proteins - metabolism Ketone Oxidoreductases - metabolism Magnetic Resonance Spectroscopy Oxidative Stress Oxygen - metabolism Propionates - metabolism propionic acid Pyruvate Synthase pyruvate:ferredoxin oxidoreductase succinic acid Succinic Acid - metabolism
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