Memory Extinction, Learning Anew, and Learning the New: Dissociations in the Molecular Machinery of Learning in Cortex

The rat insular cortex (IC) subserves the memory of conditioned taste aversion (CTA), in which a taste is associated with malaise. When the conditioned taste is unfamiliar, formation of long-term CTA memory depends on muscarinic and β-adrenergic receptors, mitogen-activated protein kinase (MAPK), an...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2001-03, Vol.291 (5512), p.2417-2419
Hauptverfasser:	Berman, Diego E., Dudai, Yadin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - pharmacology Animals Anisomycin - pharmacology b-Adrenergic receptors Behavioral psychophysiology Biological and medical sciences Brain Cerebral Cortex - metabolism Cerebral Cortex - physiology Circles Conditioning (Psychology) Experimentation Extinction, Psychological - physiology Fear Fundamental and applied biological sciences. Psychology Gustatory perception Learning Learning - physiology Learning Processes Lithium Chloride - pharmacology Long Term Memory Machine learning Male MAP Kinase Signaling System Memory Memory - physiology Memory recall Mitogen-Activated Protein Kinases - antagonists & inhibitors Mitogen-Activated Protein Kinases - metabolism Molecular biology Molecules Muscarinic Antagonists - pharmacology N methyl D aspartate receptors Neurology Neurons Neurotransmission and behavior Physiological aspects Protein Biosynthesis Protein synthesis Protein Synthesis Inhibitors - pharmacology Proteins Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Wistar Receptors Receptors, Adrenergic, beta - metabolism Receptors, Muscarinic - metabolism Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Receptors, N-Methyl-D-Aspartate - metabolism Reinforcement (Psychology) Rodents Saccharin Taste
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