HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain
: We have studied the allele distribution of DRB1, DQB1 and DPB1 loci in 80 unrelated Gypsies living in different eastern areas of the Andalusian province of Granada (southern Spain). The frequency distribution of HLA class II alleles and the genetic distance of Andalusian Gypsies from several Cauca...
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| Veröffentlicht in: | Tissue antigens 2001-02, Vol.57 (2), p.138-143 |
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| container_title | Tissue antigens |
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| creator | Ramal, L.M. De Pablo, R. Guadix, M.J. Sánchez, J. Garrido, A. Garrido, F. Jiménez-Alonso, J. López-Nevot, M.A. |
| description | : We have studied the allele distribution of DRB1, DQB1 and DPB1 loci in 80 unrelated Gypsies living in different eastern areas of the Andalusian province of Granada (southern Spain). The frequency distribution of HLA class II alleles and the genetic distance of Andalusian Gypsies from several Caucasian populations indicate a marked similarity – but not total – of the former with the Gypsy population previously studied in Madrid (central Spain), which suggests that both groups migrated together out of India. In terms of genetic distance, both Gypsy groups are more like the Czech Gypsies and the Northern Indian groups than their neighbouring Caucasian non‐Gypsy populations. In summary our data support the hypothesis of a common anthropological origin of all three European Gypsy groups, which probably split up after their arrival in Europe. |
| doi_str_mv | 10.1034/j.1399-0039.2001.057002138.x |
| format | Article |
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The frequency distribution of HLA class II alleles and the genetic distance of Andalusian Gypsies from several Caucasian populations indicate a marked similarity – but not total – of the former with the Gypsy population previously studied in Madrid (central Spain), which suggests that both groups migrated together out of India. In terms of genetic distance, both Gypsy groups are more like the Czech Gypsies and the Northern Indian groups than their neighbouring Caucasian non‐Gypsy populations. In summary our data support the hypothesis of a common anthropological origin of all three European Gypsy groups, which probably split up after their arrival in Europe.</description><identifier>ISSN: 0001-2815</identifier><identifier>EISSN: 1399-0039</identifier><identifier>DOI: 10.1034/j.1399-0039.2001.057002138.x</identifier><identifier>PMID: 11260508</identifier><language>eng</language><publisher>Copenhagen: Munksgaard International Publishers</publisher><subject>Alleles ; Andalusian Gypsies ; class II haplotypes ; Gene Frequency ; Genetic Variation ; Genetics, Population ; Haplotypes ; Histocompatibility Antigens Class II - genetics ; histocompatibility locus HLA ; HLA class II ; HLA-DP Antigens - genetics ; HLA-DP beta-Chains ; HLA-DQ Antigens - genetics ; HLA-DQ beta-Chains ; HLA-DR Antigens - genetics ; HLA-DRB1 Chains ; Humans ; Roma - genetics ; sequence-based typing ; Spain</subject><ispartof>Tissue antigens, 2001-02, Vol.57 (2), p.138-143</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4486-5c5fce1c02f2ec92870c2f9a1175023e8fb0b12bd5ee04d8c460123073915dc43</citedby><cites>FETCH-LOGICAL-c4486-5c5fce1c02f2ec92870c2f9a1175023e8fb0b12bd5ee04d8c460123073915dc43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1034%2Fj.1399-0039.2001.057002138.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1034%2Fj.1399-0039.2001.057002138.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11260508$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ramal, L.M.</creatorcontrib><creatorcontrib>De Pablo, R.</creatorcontrib><creatorcontrib>Guadix, M.J.</creatorcontrib><creatorcontrib>Sánchez, J.</creatorcontrib><creatorcontrib>Garrido, A.</creatorcontrib><creatorcontrib>Garrido, F.</creatorcontrib><creatorcontrib>Jiménez-Alonso, J.</creatorcontrib><creatorcontrib>López-Nevot, M.A.</creatorcontrib><title>HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain</title><title>Tissue antigens</title><addtitle>Tissue Antigens</addtitle><description>: We have studied the allele distribution of DRB1, DQB1 and DPB1 loci in 80 unrelated Gypsies living in different eastern areas of the Andalusian province of Granada (southern Spain). The frequency distribution of HLA class II alleles and the genetic distance of Andalusian Gypsies from several Caucasian populations indicate a marked similarity – but not total – of the former with the Gypsy population previously studied in Madrid (central Spain), which suggests that both groups migrated together out of India. In terms of genetic distance, both Gypsy groups are more like the Czech Gypsies and the Northern Indian groups than their neighbouring Caucasian non‐Gypsy populations. In summary our data support the hypothesis of a common anthropological origin of all three European Gypsy groups, which probably split up after their arrival in Europe.</description><subject>Alleles</subject><subject>Andalusian Gypsies</subject><subject>class II haplotypes</subject><subject>Gene Frequency</subject><subject>Genetic Variation</subject><subject>Genetics, Population</subject><subject>Haplotypes</subject><subject>Histocompatibility Antigens Class II - genetics</subject><subject>histocompatibility locus HLA</subject><subject>HLA class II</subject><subject>HLA-DP Antigens - genetics</subject><subject>HLA-DP beta-Chains</subject><subject>HLA-DQ Antigens - genetics</subject><subject>HLA-DQ beta-Chains</subject><subject>HLA-DR Antigens - genetics</subject><subject>HLA-DRB1 Chains</subject><subject>Humans</subject><subject>Roma - genetics</subject><subject>sequence-based typing</subject><subject>Spain</subject><issn>0001-2815</issn><issn>1399-0039</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkU2L2zAQhkXp0s3u9i8UHUpPtTsjWbYFvYTQZgPp7mFTCnsRsixTpf5ILZvG_35lEtJjKXMYhnnnETwi5D1CjMCTT_sYuZQRAJcxA8AYRAbAkOfx8RVZXJavyQLCOmI5imty4_0-TEkm5RtyjchSEJAvyO5-u6Sm1t7TzYbqura1paXzQ--KcXBdS11Lh5-WrqeDn6jpmmZs3TDRrqLLttT16J3-SH03hlDf0qeDdu0duap07e3bc78l379-2a3uo-3jerNabiOTJHkaCSMqY9EAq5g1kuUZGFZJjZgJYNzmVQEFsqIU1kJS5iZJARmHjEsUpUn4Lflw4h767vdo_aAa542ta93abvQqS6UEDDL-FcQ8FMqZ-PkUNH3nfW8rdehdo_tJIahZv9qr2bCaDatZv7roV8dw_u78zlg0tvx7fPYdAqtT4I-r7fRfcLVbPoSJQRoo0YkS_skeLxTd_1JpxjOhfjys1bPg39bPKaiUvwDZ0KKh</recordid><startdate>200102</startdate><enddate>200102</enddate><creator>Ramal, L.M.</creator><creator>De Pablo, R.</creator><creator>Guadix, M.J.</creator><creator>Sánchez, J.</creator><creator>Garrido, A.</creator><creator>Garrido, F.</creator><creator>Jiménez-Alonso, J.</creator><creator>López-Nevot, M.A.</creator><general>Munksgaard International Publishers</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>200102</creationdate><title>HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain</title><author>Ramal, L.M. ; De Pablo, R. ; Guadix, M.J. ; Sánchez, J. ; Garrido, A. ; Garrido, F. ; Jiménez-Alonso, J. ; López-Nevot, M.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4486-5c5fce1c02f2ec92870c2f9a1175023e8fb0b12bd5ee04d8c460123073915dc43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Alleles</topic><topic>Andalusian Gypsies</topic><topic>class II haplotypes</topic><topic>Gene Frequency</topic><topic>Genetic Variation</topic><topic>Genetics, Population</topic><topic>Haplotypes</topic><topic>Histocompatibility Antigens Class II - genetics</topic><topic>histocompatibility locus HLA</topic><topic>HLA class II</topic><topic>HLA-DP Antigens - genetics</topic><topic>HLA-DP beta-Chains</topic><topic>HLA-DQ Antigens - genetics</topic><topic>HLA-DQ beta-Chains</topic><topic>HLA-DR Antigens - genetics</topic><topic>HLA-DRB1 Chains</topic><topic>Humans</topic><topic>Roma - genetics</topic><topic>sequence-based typing</topic><topic>Spain</topic><toplevel>online_resources</toplevel><creatorcontrib>Ramal, L.M.</creatorcontrib><creatorcontrib>De Pablo, R.</creatorcontrib><creatorcontrib>Guadix, M.J.</creatorcontrib><creatorcontrib>Sánchez, J.</creatorcontrib><creatorcontrib>Garrido, A.</creatorcontrib><creatorcontrib>Garrido, F.</creatorcontrib><creatorcontrib>Jiménez-Alonso, J.</creatorcontrib><creatorcontrib>López-Nevot, M.A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Tissue antigens</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ramal, L.M.</au><au>De Pablo, R.</au><au>Guadix, M.J.</au><au>Sánchez, J.</au><au>Garrido, A.</au><au>Garrido, F.</au><au>Jiménez-Alonso, J.</au><au>López-Nevot, M.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain</atitle><jtitle>Tissue antigens</jtitle><addtitle>Tissue Antigens</addtitle><date>2001-02</date><risdate>2001</risdate><volume>57</volume><issue>2</issue><spage>138</spage><epage>143</epage><pages>138-143</pages><issn>0001-2815</issn><eissn>1399-0039</eissn><abstract>: We have studied the allele distribution of DRB1, DQB1 and DPB1 loci in 80 unrelated Gypsies living in different eastern areas of the Andalusian province of Granada (southern Spain). The frequency distribution of HLA class II alleles and the genetic distance of Andalusian Gypsies from several Caucasian populations indicate a marked similarity – but not total – of the former with the Gypsy population previously studied in Madrid (central Spain), which suggests that both groups migrated together out of India. In terms of genetic distance, both Gypsy groups are more like the Czech Gypsies and the Northern Indian groups than their neighbouring Caucasian non‐Gypsy populations. In summary our data support the hypothesis of a common anthropological origin of all three European Gypsy groups, which probably split up after their arrival in Europe.</abstract><cop>Copenhagen</cop><pub>Munksgaard International Publishers</pub><pmid>11260508</pmid><doi>10.1034/j.1399-0039.2001.057002138.x</doi><tpages>6</tpages></addata></record> |
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| subjects | Alleles Andalusian Gypsies class II haplotypes Gene Frequency Genetic Variation Genetics, Population Haplotypes Histocompatibility Antigens Class II - genetics histocompatibility locus HLA HLA class II HLA-DP Antigens - genetics HLA-DP beta-Chains HLA-DQ Antigens - genetics HLA-DQ beta-Chains HLA-DR Antigens - genetics HLA-DRB1 Chains Humans Roma - genetics sequence-based typing Spain |
| title | HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain |
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