A monoclonal antibody specific for a carbohydrate epitope recognizes an IgE-binding determinant shared by taxonomically unrelated allergenic pollens

Carbohydrate epitopes are capable of binding human IgE from allergic subjects and these epitopes play a role in the cross‐reactivity between allergens from unrelated sources. A monoclonal antibody (5E6), specific for a carbohydrate epitope detectable on components of Cupressus arizonica pollen extra...

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Veröffentlicht in:	Clinical and experimental allergy 2001-03, Vol.31 (3), p.458-465
Hauptverfasser:	Iacovacci, P., Pini, C., Afferni, C., Barletta, B., Tinghino, R., Schininà, E., Federico, R., Mari, A., Di Felice, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	allergen Allergens - immunology Allergic diseases Animals Antibodies, Monoclonal - immunology Antibody Specificity Biological and medical sciences carbohydrate Carbohydrates - immunology General aspects glycoprotein human serum Humans IgE IgG Immunodominant Epitopes - immunology Immunoglobulin E - immunology Immunopathology Medical sciences Mice monoclonal antibody Pollen - immunology
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