Diversity of the Killer Cell Ig-Like Receptors of Rhesus Monkeys

Because the killer cell Ig-like receptors (KIRs) have only been characterized in humans and chimpanzees, we do not have a full understanding of their evolutionary history. Therefore, cDNAs encoding the KIR molecules of five rhesus monkeys were characterized, and were found to differ from the KIR mol...

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Veröffentlicht in:	The Journal of immunology (1950) 2001-04, Vol.166 (7), p.4380-4390
Hauptverfasser:	Hershberger, Karen L, Shyam, Richa, Miura, Ayako, Letvin, Norman L
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - immunology Amino Acid Sequence Animals Cloning, Molecular Evolution, Molecular Humans Immunoglobulins - chemistry killer cell immunoglobulin-like receptors Killer Cells, Natural - immunology Killer Cells, Natural - metabolism KIR1D protein KIR3DH protein KIR3DL protein Macaca mulatta - genetics Macaca mulatta - immunology Molecular Sequence Data Protein Isoforms - chemistry Protein Isoforms - genetics Protein Isoforms - isolation & purification Receptors, Immunologic - chemistry Receptors, Immunologic - genetics Receptors, Immunologic - isolation & purification Receptors, KIR Receptors, KIR2DL4 Sequence Alignment Sequence Homology, Amino Acid
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