Role of Endothelin and Isoprostanes in Slow Pressor Responses to Angiotensin II

We tested the hypothesis that angiotensin II (Ang II)–induced stimulations of endothelin (ET) and isoprostanes are implicated in the slow pressor responses to Ang II. We infused either vehicle (group 1) or Ang II (groups 2 to 4) intravenously at 5 ng/kg per minute via osmotic pumps for 15 days into...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2001-02, Vol.37 (2, Part 2 Suppl), p.505-510
Hauptverfasser:	Ortiz, Maria Clara, Sanabria, Elisabeth, Manriquez, Melissa C, Romero, Juan C, Juncos, Luis A
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - antagonists & inhibitors Angiotensin II - blood Angiotensin II - pharmacology Angiotensin Receptor Antagonists Animals Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure - drug effects Bosentan Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Endothelins - antagonists & inhibitors Endothelins - blood Endothelins - metabolism Glomerular Filtration Rate Infusions, Intravenous Losartan - pharmacology Medical sciences Nitrites - blood Nitrites - urine Prostaglandins - blood Prostaglandins - metabolism Rats Rats, Sprague-Dawley Receptor, Angiotensin, Type 1 Receptor, Angiotensin, Type 2 Receptors, Angiotensin - metabolism Sulfonamides - pharmacology
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