Age-dependent decline in bone nodule formation stimulating activity in rat serum is mainly due to the change in the corticosterone level

The replacement of fetal bovine serum with rat serum in a culture medium brought about a marked increase in the formation of mineralized bone nodules (BN) in primary cultures of rat calvarial cells. These effects of rat serum were most prominent when added during the early phase of the culture, indi...

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Veröffentlicht in:Journal of cellular biochemistry 2001-01, Vol.81 (3), p.547-556
Hauptverfasser: Fujieda, Masaki, Takao, Noriaki, Kiriu, Michiaki, Mizuochi, Shigeki, Kaneki, Hiroyuki, Ide, Hayao
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Sprache:eng
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