Effects of clodronate on vertebral fracture risk in osteoporosis: a 1-year interim analysis

Effects of clodronate on vertebral fracture risk in osteoporosis: a 1-year interim analysis

The aim of this study was to determine whether clodronate reduced the incidence of vertebral fractures in patients with osteoporosis. We report here the interim analysis after 1 year of a 3-year double-blind placebo-controlled study. The objectives of the interim analysis were to determine whether t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bone (New York, N.Y.) N.Y.), 2001-03, Vol.28 (3), p.310-315
Hauptverfasser: McCloskey, E, Selby, P, de Takats, D, Bernard, J, Davies, M, Robinson, J, Francis, R, Adams, J, Pande, K, Beneton, M, Jalava, T, Löyttyniemi, E, Kanis, J.A
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Bone Density
Bones, joints and connective tissue. Antiinflammatory agents
Clodronate
Clodronic Acid - therapeutic use
Female
Humans
Incidence
Male
Medical sciences
Osteoporosis
Osteoporosis - complications
Pharmacology. Drug treatments
Risk Assessment
Secondary osteoporosis
Spinal Fractures - epidemiology
Spinal Fractures - etiology
Spinal Fractures - prevention & control
United Kingdom - epidemiology
Vertebral fracture
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The aim of this study was to determine whether clodronate reduced the incidence of vertebral fractures in patients with osteoporosis. We report here the interim analysis after 1 year of a 3-year double-blind placebo-controlled study. The objectives of the interim analysis were to determine whether there was a trend in fracture frequency and to examine the effects of clodronate on bone mineral density (BMD). Patients with densitometrically proven osteoporosis (T-score
ISSN:8756-3282
1873-2763
DOI:10.1016/S8756-3282(00)00437-3